HTN risk up for african-american live kidney donors

HTN risk up for african-american live kidney donors
African-American live kidney donors have a significantly increased risk of hypertension compared with non-donors, according to a study published online Oct. 24 in the American Journal of Transplantation.

(HealthDay)—African-American live kidney donors have a significantly increased risk of hypertension compared with non-donors, according to a study published online Oct. 24 in the American Journal of Transplantation.

To examine the risk of hypertension and kidney disease in donors, Mona D. Doshi, M.D., of Wayne State University in Detroit, and associates evaluated 103 African-American live kidney donors, who donated between 1993 and 2006 at two transplant centers, and 235 matched non-donors from the Coronary Artery Risk Development in Young Adults prospective cohort study. Donors and non-donors were followed for a mean of 6.8 or 6.4 years, respectively.

The researchers found that donors had a significantly increased hypertension risk compared with non-donors (40.8 versus 17.9 percent; relative risk, 2.4). Just over half (52.4 percent) of the donors with hypertension were untreated. Of the donors, 15.5 percent had an estimated <60 mL/min/1.73 m², 5.8 percent had microalbuminuria, and none of them were on dialysis.

"The data from our retrospective study demonstrates that live is associated with increased risk of hypertension in African-Americans," the authors write. "At this time, results of the current study should not dissuade African-Americans from being a live , but does raise awareness about the importance of donor follow-up."

One of the authors disclosed financial ties to the pharmaceutical industry.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Never too old to donate a kidney?

Oct 28, 2011

People over age 70 years of age can safely donate a kidney, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results provide good news for patients ...

Recommended for you

What are the chances that your dad isn't your dad?

23 hours ago

How confident are you that the man you call dad is really your biological father? If you believe some of the most commonly-quoted figures, you could be forgiven for not being very confident at all. But how ...

New technology that is revealing the science of chewing

Apr 15, 2014

CSIRO's 3D mastication modelling, demonstrated for the first time in Melbourne today, is starting to provide researchers with new understanding of how to reduce salt, sugar and fat in food products, as well ...

After skin cancer, removable model replaces real ear

Apr 11, 2014

(HealthDay)—During his 10-year struggle with basal cell carcinoma, Henry Fiorentini emerged minus his right ear, and minus the hearing that goes with it. The good news: Today, the 56-year-old IT programmer ...

Italy scraps ban on donor-assisted reproduction

Apr 09, 2014

Italy's Constitutional Court on Wednesday struck down a Catholic Church-backed ban against assisted reproduction with sperm or egg donors that has forced thousands of sterile couples to seek help abroad.

User comments