New study finds link between overfeeding and high blood pressure
(Medical Xpress)—A new study conducted by researchers at Lehman College, and recently published in the American Heart Association's journal Hypertension, shows conclusively that overfeeding causes increases in sympathetic nerve activity (SNA)—part of the fight or flight reflex—which can lead to the development of high blood pressure. Dr. Martin Muntzel, a professor in the College's Dept. of Biology and an expert on diet, Type 2 diabetes and high blood pressure, led the study.
For years, scientists have known that obesity and weight gain are the major causes of high blood pressure, but they haven't been able to determine how this happens. To find out, Dr. Muntzel and his team implanted radiotelemetry devises into fourteen female Wistar rats to monitor SNA, heart rate and arterial pressure. This experiment marks the first successful use of radiotelemetry technology in rats.
Over a three-week period, the researchers fed seven of the rats a diet high in fat that included vanilla wafers, crackers, buttered popcorn, cheetos and other high-caloric nutrients, while the other seven rats were fed a low-fat diet. The results were immediate—within fifteen days the rats consuming the high-fat diet gained weight and their fat mass doubled, activating lumbar SNA, which in turn caused their heart rate and blood pressure to rise.
"One thing that really surprised me through the course of this experiment is that just two weeks of consuming junk food doubled the subject's fat mass," says Dr. Muntzel. The team chose the cafeteria-style diet not only for its palatability and high caloric content, but also because they knew that it would have precisely the effect they wanted, which was rapid weight gain.
"None of this would have been possible had we not been able to attain the radiotelemetry technology," explains Dr. Muntzel. Telemetry-based devices, specifically the kind that records SNA, have been in use for only four years. "There are a number of researchers from around the world that are using this, but our group was the first to actually make it work in rats," he adds proudly.
More information: hyper.ahajournals.… 498.abstract
Journal reference: Hypertension
Provided by City College of New York
- Weight gain induced by high-fat diet increases active-period sleep and sleep fragmentation Jul 10, 2012 | not rated yet | 0
- Fat substitutes linked to weight gain Jun 20, 2011 | not rated yet | 0
- Greater diet-induced obesity in rats consuming sugar solution during the inactive period Jul 10, 2012 | not rated yet | 0
- Early childhood diet may influence future health Jan 14, 2009 | not rated yet | 0
- New study highlights perils of snack-filled diet Jun 17, 2011 | not rated yet | 0
- Motion perception revisited: High Phi effect challenges established motion perception assumptions Apr 23, 2013 | 3 / 5 (2) | 2
- Anything you can do I can do better: Neuromolecular foundations of the superiority illusion (Update) Apr 02, 2013 | 4.5 / 5 (11) | 5
- The visual system as economist: Neural resource allocation in visual adaptation Mar 30, 2013 | 5 / 5 (2) | 9
- Separate lives: Neuronal and organismal lifespans decoupled Mar 27, 2013 | 4.9 / 5 (8) | 0
- Sizing things up: The evolutionary neurobiology of scale invariance Feb 28, 2013 | 4.8 / 5 (10) | 14
Classical and Quantum Mechanics via Lie algebras
Apr 15, 2011 I'd like to open a discussion thread for version 2 of the draft of my book ''Classical and Quantum Mechanics via Lie algebras'', available online at http://lanl.arxiv.org/abs/0810.1019 , and for the...
- More from Physics Forums - Independent Research
More news stories
The gap between life expectancy in patients with a mental illness and the general population has widened since 1985 and efforts to reduce this gap should focus on improving physical health, suggest researchers in a paper ...
Health 6 hours ago | not rated yet | 0
Failure to use linked electronic health records may lead to biased estimates of heart attack incidence and outcome, warn researchers in a paper published in BMJ today.
Health 6 hours ago | not rated yet | 0
Dietary advice on added sugar is damaging our health, warns a cardiologist in BMJ today. Dr. Aseem Malhotra believes that "not only has this advice been manipulated by the food industry for profit but it is actually a risk ...
Health 6 hours ago | 5 / 5 (4) | 0
(HealthDay)—In 2008 to 2010, the prevalence of key health behaviors among U.S. adults varied, with about one in five adults current smokers and 62.1 percent overweight or obese, according to a report presented ...
Health 9 hours ago | 5 / 5 (1) | 0
(HealthDay)—The overall health of Americans isn't improving much, with about six in 10 people either overweight or obese and large numbers engaging in unhealthy behaviors like smoking, heavy drinking or ...
Health 9 hours ago | not rated yet | 0
13 hours ago | 4.2 / 5 (5) | 0 |
11 hours ago | 4.9 / 5 (9) | 0 |
7 hours ago | 3 / 5 (2) | 0
8 hours ago | 5 / 5 (3) | 0 |
13 hours ago | 4.5 / 5 (6) | 0 |
9 hours ago | 5 / 5 (1) | 0 |