Estrogen levels tied to risk for sudden cardiac death in study

May 11, 2013
Estrogen levels tied to risk for sudden cardiac death in study
Tests reveal higher concentration of the sex hormone in women and men.

(HealthDay)—Higher levels of the hormone estrogen are associated with an increased risk of sudden cardiac death in men and women, a new study suggests.

can occur when the heart suddenly and unexpectedly stops beating (sudden cardiac arrest). Each year in the United States, more than 350,000 people die of sudden cardiac death.

Researchers examined data from people in Portland, Ore., who suffered sudden cardiac death or had . Tests of plasma taken at the time of death or during a doctor's visit indicated that both groups had a similar proportion of common heart risk factors such as diabetes, obesity, high blood pressure and high cholesterol.

But levels of testosterone were much lower among men and slightly higher among women in the sudden cardiac death group compared to those with coronary artery disease, according to the study, which is scheduled for presentation Friday at the annual meeting of the Heart Rhythm Society in Denver.

The researchers also found that were much higher and the testosterone-to-estrogen ratio was lower in both men and women who suffered sudden cardiac death. This did not, however, prove a cause-and-effect link between higher estrogen levels and sudden cardiac death.

The findings could help identify patients at risk for and death, Dr. Sumeet Chugh, associate director for genomic cardiology and director of the Heart Rhythm Center at the Cedars Sinai Heart Institute in Los Angeles, said in a Heart Rhythm Society news release.

Studies presented at meetings are considered preliminary until published in a peer-reviewed medical journal.

Explore further: Predictors of dying suddenly versus surviving heart attack identified

More information: The U.S. National Heart, Lung, and Blood Institute has more about sudden cardiac arrest.

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