Delayed skin closure may reduce surgical infection

Delayed skin closure may reduce surgical infection
Delayed primary skin closure may reduce the risk of infection after surgery, but the current studies are not definitive due to poor design, according to the results of a meta-analysis published online June 26 in JAMA Surgery.

(HealthDay)—Delayed primary skin closure may reduce the risk of infection after surgery, but the current studies are not definitive due to poor design, according to the results of a meta-analysis published online June 26 in JAMA Surgery.

Aneel Bhangu, M.B.Ch.B., from the Royal Centre for Defence Medicine in Birmingham, U.K., and colleagues identified and performed a meta-analysis of eight published studies in which 623 patients with contaminated or dirty abdominal were randomized to delayed primary skin closure or primary skin closure.

The researchers found that 77.4 percent of patients had appendicitis, followed by perforated abdominal viscus, ileostomy closure, , and intra-abdominal abscess or other peritonitis. For delayed closure, the time to first review was two to five days postoperatively. All studies were determined to be of poor quality, with a of bias and deficient in study design and outcome assessment. Using a fixed-effects model, delayed closure significantly reduced the risk of surgical site infection (odds ratio, 0.65), but heterogeneity was high (72 percent) and the effect was no longer significant using a random-effects model.

"Delayed primary skin closure may reduce the rate of surgical site infection, but current trials fail to provide definitive evidence because of poor design," Bhangu and colleagues conclude.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Recommended for you

Facelift surgery after massive weight loss poses challenges

Jan 29, 2015

Patients undergoing bariatric surgery for severe obesity are often left with excess, sagging skin affecting all areas of the body—including the face. The unique challenges of facelift surgery in this group of patients—and ...

Good results with surgery for gynecomastia in bodybuilders

Jan 28, 2015

With attention to some unique patient characteristics, breast reduction surgery achieves good aesthetic outcomes in bodybuilders with gynecomastia—enlargement of the male breast, according to a report in the February issue ...

Web surfing to weigh up bariatric surgery options

Jan 27, 2015

Obese people considering weight-reducing bariatric surgery are only topped by pregnant women when it comes to how often they turn to the Internet for health advice. While most use it to read up on relevant procedures and ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.