Delayed skin closure may reduce surgical infection

Delayed skin closure may reduce surgical infection
Delayed primary skin closure may reduce the risk of infection after surgery, but the current studies are not definitive due to poor design, according to the results of a meta-analysis published online June 26 in JAMA Surgery.

(HealthDay)—Delayed primary skin closure may reduce the risk of infection after surgery, but the current studies are not definitive due to poor design, according to the results of a meta-analysis published online June 26 in JAMA Surgery.

Aneel Bhangu, M.B.Ch.B., from the Royal Centre for Defence Medicine in Birmingham, U.K., and colleagues identified and performed a meta-analysis of eight published studies in which 623 patients with contaminated or dirty abdominal were randomized to delayed primary skin closure or primary skin closure.

The researchers found that 77.4 percent of patients had appendicitis, followed by perforated abdominal viscus, ileostomy closure, , and intra-abdominal abscess or other peritonitis. For delayed closure, the time to first review was two to five days postoperatively. All studies were determined to be of poor quality, with a of bias and deficient in study design and outcome assessment. Using a fixed-effects model, delayed closure significantly reduced the risk of surgical site infection (odds ratio, 0.65), but heterogeneity was high (72 percent) and the effect was no longer significant using a random-effects model.

"Delayed primary skin closure may reduce the rate of surgical site infection, but current trials fail to provide definitive evidence because of poor design," Bhangu and colleagues conclude.

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Recommended for you

New software helps improve surgical safety

date Apr 13, 2015

Because the spine is made up of repeating elements that look alike, surgeons can mistakenly operate on the wrong vertebra. To avoid this, Johns Hopkins researchers have developed a software program that works ...

Can facial plastic surgery make you more likeable?

date Apr 09, 2015

Facial plastic surgery may do more than make you look youthful. It could change—for the better—how people perceive you. The first study of its kind to examine perception after plastic surgery finds that ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.