Smoking cessation, weight gain, and subsequent CHD risk

The authors used data from the Women's Health Initiative to assess the association between smoking cessation, weight gain, and subsequent coronary heart disease risk among postmenopausal women with and without diabetes.

"Cigarette smoking is an important cause of cardiovascular disease, and reduces the risk. However, weight gain after smoking cessation may increase the risk of diabetes and weaken the benefit of quitting," write Juhua Luo, Ph.D., of the Indiana University School of Public Health, Bloomington, Ind., and colleagues.

As reported in a JAMA's Research Letter, the authors used data from the Women's Health Initiative (WHI) to assess the association between smoking cessation, weight gain, and subsequent (CHD) risk among with and without diabetes. In the WHI, 161,808 postmenopausal women 50 through 79 years of age were recruited from 40 sites between 1993 and 1998 and followed up every 6 to 12 months. Women without known cancer or cardiovascular disease at baseline or CHD at year 3 were followed up until CHD diagnosis, date of death, loss to follow-up, or September 30, 2010, whichever occurred first.

Of 104,391 women followed up, 3,381 developed CHD, during an average of 8.8 years. The researchers found that smoking cessation was associated with a lower risk of CHD among postmenopausal women with and without diabetes. Weight gain following smoking cessation weakened this association, especially for women with diabetes who gained 11 lbs. or more, although power was limited in this subgroup due to the small number of cases.

More information: JAMA. 2013;310[1]:94-95

Related Stories

Snoring tied to increased cardiovascular risk in women

date Feb 14, 2013

(HealthDay)—For women, snoring is associated with a modest increased risk of stroke, coronary heart disease (CHD), and cardiovascular disease (CVD), according to a study published in the Feb. 15 issue of ...

Body Mass Index and coronary heart disease

date Apr 01, 2013

Coronary heart disease (CHD) increases with BMI, as well as with age, finds an article published in BioMed Central's open access journal BMC Medicine. The research from the Million Women Study indicates that increased weight ...

Aggressive lowering of BP may up risk of CHD in diabetes

date May 31, 2013

(HealthDay)—Aggressive lowering of blood pressure may be associated with increased risk of coronary heart disease (CHD) in black or white patients with diabetes, according to research published online May ...

Recommended for you

Clinical trial reduces stress of cancer caregivers

date 14 hours ago

Stem cell transplant is essential in the care of many blood cancers, but leaves patients requiring in-home care for months after. Frequently the role of caregiver falls to family or other committed members ...

Video: Debunking three common food myths

date 15 hours ago

You might have heard that microwaving your food is dangerous. Maybe your health nut friend told you that eating frozen veggies is less healthful than eating fresh ones. Is a glass of red wine really good ...

Tackling child abuse in Africa with research and fun

date 18 hours ago

In one of South Africa's poorest areas, an imaginative new parenting programme is tackling the physical and emotional abuse of children. Oxford University's Vice-Chancellor, Professor Andrew Hamilton, travelled ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.