Diabetic retinopathy severity inversely tied to cognition

Diabetic retinopathy severity inversely tied to cognition
For patients with type 2 diabetes, the severity of diabetic retinopathy is inversely linked to cognitive impairment, according to a study published online April 30 in Diabetes Care.

(HealthDay)—For patients with type 2 diabetes, the severity of diabetic retinopathy (DR) is inversely linked to cognitive impairment, according to a study published online April 30 in Diabetes Care.

Roxanne R. Crosby-Nwaobi, Ph.D., from King's College London, and colleagues recruited 380 patients with type 2 diabetes from a population-based program. Participants were grouped by severity of DR: no/mild DR (252 patients) or proliferative (PDR; 128 patients). Participants underwent psychosocial evaluation; ; ophthalmic and physical examination, including blood assays; and cognitive assessments.

The researchers found that there was a significant inverse correlation between the severity of DR and cognitive impairment. The observed variance was partially explained by ethnicity (16 percent), education (7.3 percent), and retinopathy status (6.8 percent). Cognitive impairment scores on the Addenbrooke's Cognitive Examination-Revised were significantly lower in the no/mild DR group versus the PDR group. Twelve percent of the no/mild DR group and 5 percent of the PDR group had positive screening results for dementia or significant cognitive impairment, based on the Mini-Mental State Examination cut-off scores.

"Patients with minimal DR demonstrated more cognitive impairment than those with advanced DR," the authors write. "The increased prevalence of cognitive impairment in diabetes may be associated with factors other than evident retinal ."

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Cardiac disease linked to higher risk of mental impairment

date Jan 28, 2013

Cardiac disease is associated with increased risk of mild cognitive impairment such as problems with language, thinking and judgment—particularly among women with heart disease, a Mayo Clinic study shows. Known as nonamnestic ...

Retinopathy severity linked to cardiovascular outcome

date Jan 25, 2013

(HealthDay)—For individuals with type 2 diabetes, incident cardiovascular outcomes are determined not only by the severity of diabetic retinopathy but also by its progression, according to research published ...

Recommended for you

Faster heart rate linked to diabetes risk

date 6 hours ago

An association between resting heart rate and diabetes suggests that heart rate measures could identify individuals with a higher future risk of diabetes, according to an international team of researchers.

EBV co-infection may boost malaria mortality in childhood

date 21 hours ago

Many people who live in sub-Saharan Africa develop a natural immunity to malaria, through repeated exposure to Plasmodium parasites. Even so, the disease kills close to half a million children per year, according ...

Three important things you didn't know about diabetes

date May 21, 2015

When we think of diabetes, we tend to think of rich people with poor lifestyles. A chronic disease linked with obesity, heart disease and worse outcomes for some infectious diseases, diabetes tends to be ...

Changes observed in HbA1c during ramadan

date May 20, 2015

(HealthDay)—For patients with type 2 diabetes, during Ramadan, the greatest change among metabolic parameters is seen for glycemia, according to a study published online May 13 in the Journal of Diabetes In ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.