Review defines new fracture risk factors post-vertebroplasty

Review defines new fracture risk factors post-vertebroplasty
Patients with low bone mineral density, low body mass index, and intradiscal cement leakage are at risk for new osteoporotic vertebral compression fractures after vertebroplasty, according to a review published in the June issue of the Journal of Spinal Disorders & Techniques.

(HealthDay)—Patients with low bone mineral density (BMD), low body mass index (BMI), and intradiscal cement leakage are at risk for new osteoporotic vertebral compression fractures (VCFs) after vertebroplasty, according to a review published in the June issue of the Journal of Spinal Disorders & Techniques.

Zitao Zhang, Ph.D., from The First Affiliated Hospital of Nanjing Medical University in China, and colleagues conducted a systematic review and meta-analysis to examine risk factors for new osteoporotic VCFs following . Sixteen studies comprising 559 cases and 1,736 controls were included in the analyses.

The researchers found that low BMD (standardized mean difference [SMD], ?0.73); low BMI (SMD, ?0.30); and intradiscal cement leakage (odds ratio [OR], 2.13) were significant risk factors for new VCFs. These were also significant risk factors for new VCFs adjacent to the treated VCF (SMD, ?0.43; SMD, ?0.52; and OR, 2.61, respectively). For new VCFs away from the original VCF, none of low BMD, low BMI, intradiscal cement leakage, cement volume, surgical approach, age, sex, or thoracolumbar junction fracture were significant risk factors. Dynamic characteristics were reported as risk factors for new VCFs in one study.

"The results of this meta-analysis strongly suggested that patients with low BMD, low BMI, and intradiscal cement leakage were at high risk for new VCFs after vertebroplasty, and risk-reduction options should be considered for such patients," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Kyphoplasty superior to vertebroplasty for vertebral fx

Aug 27, 2012

(HealthDay)—For people with osteoporotic vertebral compression fractures, kyphoplasty (KP) is superior to vertebroplasty (VP) for correcting kyphosis, restoring vertebral height, and preventing leakage ...

Recommended for you

Ebola-hit Liberia delays school reopening

2 hours ago

Liberia's education ministry said on Sunday it had postponed by two weeks the reopening of the country's schools, which were closed six months ago to limit the spread of the Ebola virus.

Ebola: timeline of a ruthless killer

11 hours ago

Here are key dates in the current Ebola epidemic, the worst ever outbreak of the haemorrhagic fever which first surfaced in 1976 in the Democratic Republic of Congo (DRC).

Ebola reveals shortcomings of African solidarity

Jan 31, 2015

As Africa's leaders meet in Ethiopia to discuss the Ebola crisis, expectations of firm action will be tempered by criticism over the continent's poor record in the early stages of the epidemic.

Second bird flu case confirmed in Canada

Jan 30, 2015

The husband of a Canadian who was diagnosed earlier this week with bird flu after returning from a trip to China has also tested positive for the virus, health officials said Friday.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.