Post-breast cancer, metformin has no effect on mortality

July 3, 2013
Post-breast cancer, metformin has no effect on mortality
For older women with diabetes and breast cancer, there is no association between metformin use and all-cause or breast cancer-specific mortality, according to a study published online April 30 in Diabetes Care.

(HealthDay)—For older women with diabetes and breast cancer, there is no association between metformin use and all-cause or breast cancer-specific mortality, according to a study published online April 30 in Diabetes Care.

Iliana C. Lega, M.D., from the Women's College Hospital in Toronto, and colleagues conducted a population-based study involving 2,361 women aged 66 years or older diagnosed with diabetes and . The correlation between cumulative duration of past use and all-cause and breast cancer-specific mortality was assessed.

During a mean follow-up of 4.5 years, the researchers identified 1,101 deaths (46.6 percent), of which 16.3 percent were breast cancer-specific. There was no significant association observed between cumulative duration of past metformin use and all-cause or breast cancer-specific mortality.

"In summary, we conducted a large population-based study to investigate the effects of metformin therapy on mortality after breast cancer in a diabetic population," the authors write. "Cumulative exposure of metformin was not significantly associated with all-cause or breast cancer-specific mortality in our incident diabetic cohort when modeled as a time-varying covariate."

Explore further: Metformin may have dual effect in breast cancer

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talatmahmud
not rated yet Jul 04, 2013
This is as usual informative writing like before on breast cancer. This has helped me to justify the cell division during the breast cancer. I will continue reading with this site on breast cancer. This cancer cell's division is so fast and can spread within a short time for this reason. I have also collected some other information other sites.
Thanks.

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