Prevalence of poorer kidney function increases among adults 80 years of age and older

September 24, 2013

Recent studies have shown that older adults with chronic kidney disease (CKD; defined as an estimated glomerular filtration rate [GFR; a measure of kidney function] of less than 60 mL/min/1.73 m2) have a high prevalence of concurrent complications and increased risk for adverse outcomes including mortality, cardiovascular disease, and kidney failure. A prior study demonstrated an increase in CKD prevalence between 1988-1994 and 1999-2004 for the general U.S. population. However, trends in CKD prevalence have not been reported for the oldest old [defined as 80 years of age or older]," write C. Barrett Bowling, M.D., M.S.P.H., formerly of the Veterans Affairs Medical Center, Atlanta, and colleagues.

As reported in a Research Letter, the authors used data from national surveys (the National Health and Nutrition Examination Surveys (NHANES) 1988-1994 and 1999-2010), to study participants age 80 years or older who completed a medical evaluation in the NHANES mobile examination center (n = 3,558).

The researchers found that the prevalence of an estimated GFR of less than 60 mL/min/1.73 m2 was 40.5 percent in 1988-1994, 49.9 percent in 1999-2004, and 51.2 percent in 2005-2010. The prevalence of a more severe reduction in estimated GFR (less than 45 mL/min/1.73 m2) was 14.3 percent in 1988-1994, 18.6 percent in 1999-2004, and 21.7 percent in 2005-2010.

The findings point to a rise in prevalence in CKD among people 80 years and older and suggests that "efforts to address CKD among the oldest old may be necessary," the authors conclude.

Explore further: Moderate kidney disease costs medicare tens of billions of dollars each year

More information: doi:10.l001/jama.2013.252441

Related Stories

Pediatric kidney disease tied to abnormal carotid arteries

September 28, 2012

(HealthDay)—Ultrasound measurements of carotid intima-media thickness (cIMT) are significantly elevated among children with chronic kidney disease (CKD) compared with healthy controls, according to a study published online ...

New, combined equation more accurately estimates GFR

July 6, 2012

(HealthDay) -- A combined creatinine-cystatin C equation has improved performance and accuracy for estimating glomerular filtration rate (GFR), according to research published in the July 5 issue of the New England Journal ...

Prevalence of gout increases with increasing BMI

July 17, 2012

(HealthDay) -- Having an increased body mass index (BMI) correlates with increased prevalence of gout in adults, according to study published online July 6 in Arthritis Care & Research.

Recommended for you

Zika virus infection alters human and viral RNA

October 20, 2016

Researchers at University of California San Diego School of Medicine have discovered that Zika virus infection leads to modifications of both viral and human genetic material. These modifications—chemical tags known as ...

Food-poisoning bacteria may be behind Crohn's disease

October 19, 2016

People who retain a particular bacterium in their gut after a bout of food poisoning may be at an increased risk of developing Crohn's disease later in life, according to a new study led by researchers at McMaster University.

Neurodevelopmental model of Zika may provide rapid answers

October 19, 2016

A newly published study from researchers working in collaboration with the Regenerative Bioscience Center at the University of Georgia demonstrates fetal death and brain damage in early chick embryos similar to microcephaly—a ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.