Radiographic findings mirror clinical severity in H7N9 flu

Radiographic findings mirror clinical severity in H7N9 flu
In patients with novel avian-origin influenza A H7N9 virus infection, radiological findings mirror the severity of the clinical presentation, according to a study published in the September issue of Radiology.

(HealthDay)—In patients with novel avian-origin influenza A H7N9 virus infection, radiological findings mirror the severity of the clinical presentation, according to a study published in the September issue of Radiology.

Qingle Wang, M.D., from Shanghai Medical College of Fudan University, and colleagues evaluated 12 patients (nine men and three women) with novel avian-origin influenza A H7N9 using chest radiography and thin-section computed tomography (CT). Two chest radiologists examined the images together with clinical data and investigated lesion patterns, distributions, and changes at follow-up.

The researchers found that all patients had progressing infection of the at presentation, with fever, cough, and shortness of breath that progressed to acute . On imaging, findings included ground-glass opacities (GGOs; 12 patients); consolidations, air bronchograms, and interlobular septal thickening (11 patients each); centrilobular nodules and reticulations (seven patients each); cystic changes (four patients); and bronchial dilatation and subpleural linear opacities (three patients each). In all cases, the involved at least three lobes, and in 11 patients these were detected in the right lower lobe. At follow-up CT performed in 10 patients, interval improvement of the lesions was seen in three patients, while seven patients had worsening. The overall clinical severity of the disease was closely reflected in imaging findings.

"Rapidly progressive GGOs and consolidations with air bronchograms and interlobular septal thickening, with right lower lobe predominance, are the main imaging findings in H7N9 pneumonia," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

New study describes imaging findings in H7N9 influenza

Jul 02, 2013

H7N9 pneumonia is characterized by imaging findings that differentiate it from other types of pneumonia, including rapidly progressive changes in the lungs and pulmonary connective tissues, according to the first study to ...

Most with confirmed H7N9 avian flu are critically ill

Apr 25, 2013

(HealthDay)—Most Chinese patients with confirmed avian influenza A (H7N9) are critically ill and 21 percent have died, according to a preliminary report published online April 24 in the New England Journal of ...

Recommended for you

US looking past Ebola to prepare for next outbreak

6 hours ago

The next Ebola or the next SARS. Maybe even the next HIV. Even before the Ebola epidemic in West Africa is brought under control, U.S. public health officials are girding for the next health disaster.

Can robots help stop the Ebola outbreak?

15 hours ago

The US military has enlisted a new germ-killing weapon in the fight against Ebola—a four-wheeled robot that can disinfect a room in minutes with pulses of ultraviolet light.

New bird flu case in Germany

15 hours ago

A worrying new strain of bird flu has been observed for the first time in a wild bird in northern Germany, the agriculture ministry said Saturday.

Mali announces new Ebola case

Nov 22, 2014

Mali announced Saturday a new case of Ebola in a man who is fighting for his life in an intensive care unit in the capital Bamako.

Plague outbreak kills 40 in Madagascar: WHO

Nov 22, 2014

An outbreak of plague has killed 40 people in Madagascar, the World Health Organization said, warning that the disease could spread rapidly in the country's densely populated capital Antananarivo.

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.