Radiographic findings mirror clinical severity in H7N9 flu

September 11, 2013
Radiographic findings mirror clinical severity in H7N9 flu
In patients with novel avian-origin influenza A H7N9 virus infection, radiological findings mirror the severity of the clinical presentation, according to a study published in the September issue of Radiology.

(HealthDay)—In patients with novel avian-origin influenza A H7N9 virus infection, radiological findings mirror the severity of the clinical presentation, according to a study published in the September issue of Radiology.

Qingle Wang, M.D., from Shanghai Medical College of Fudan University, and colleagues evaluated 12 patients (nine men and three women) with novel avian-origin influenza A H7N9 using chest radiography and thin-section computed tomography (CT). Two chest radiologists examined the images together with clinical data and investigated lesion patterns, distributions, and changes at follow-up.

The researchers found that all patients had progressing infection of the at presentation, with fever, cough, and shortness of breath that progressed to acute . On imaging, findings included ground-glass opacities (GGOs; 12 patients); consolidations, air bronchograms, and interlobular septal thickening (11 patients each); centrilobular nodules and reticulations (seven patients each); cystic changes (four patients); and bronchial dilatation and subpleural linear opacities (three patients each). In all cases, the involved at least three lobes, and in 11 patients these were detected in the right lower lobe. At follow-up CT performed in 10 patients, interval improvement of the lesions was seen in three patients, while seven patients had worsening. The overall clinical severity of the disease was closely reflected in imaging findings.

"Rapidly progressive GGOs and consolidations with air bronchograms and interlobular septal thickening, with right lower lobe predominance, are the main imaging findings in H7N9 pneumonia," the authors write.

Explore further: New study describes imaging findings in H7N9 influenza

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

New study describes imaging findings in H7N9 influenza

July 2, 2013

H7N9 pneumonia is characterized by imaging findings that differentiate it from other types of pneumonia, including rapidly progressive changes in the lungs and pulmonary connective tissues, according to the first study to ...

Most with confirmed H7N9 avian flu are critically ill

April 25, 2013

(HealthDay)—Most Chinese patients with confirmed avian influenza A (H7N9) are critically ill and 21 percent have died, according to a preliminary report published online April 24 in the New England Journal of Medicine.

Recommended for you

Zika in fetal brain tissue responds to a popular antibiotic

November 30, 2016

Working in the lab, UC San Francisco researchers have identified fetal brain tissue cells that are targeted by the Zika virus and determined that azithromycin, a common antibiotic regarded as safe for use during pregnancy, ...

Zika and glaucoma linked for first time in new study

November 30, 2016

A team of researchers in Brazil and at the Yale School of Public Health has published the first report demonstrating that the Zika virus can cause glaucoma in infants who were exposed to the virus during gestation.

Flu forecasts successful on neighborhood level

November 30, 2016

Scientists at Columbia University's Mailman School of Public Health developed a computer model to predict the onset, duration, and magnitude of influenza outbreaks for New York City boroughs and neighborhoods. They found ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.