Nerve root sedimentation sign for spinal stenosis assessed

Nerve root sedimentation sign for spinal stenosis assessed

(HealthDay)—The nerve root sedimentation sign (SedSign), seen on magnetic resonance images, can differentiate lumbar spinal stenosis (LSS) from asymptomatic controls, according to a study published in the Nov. 15 issue of Spine.

Christy C. Tomkins-Lane, Ph.D., from Mount Royal University in Calgary, Canada, and colleagues examined the sensitivity and specificity of the SedSign in a retrospective study involving three blinded raters who independently reviewed from 67 subjects with clinically diagnosed LSS confirmed on imaging by a spine specialist; 31 people with low back pain (LBP) but no LSS; four people with severe vascular claudication; and 46 asymptomatic participants.

The researchers found that inter-rater reliability ranged from 0.62 to 0.69 and intrarater reliability for the sign ranged from κ = 0.87 to 0.97. Sensitivity and specificity ranged from 42 to 66 percent and 49 to 78 percent, respectively. Inclusion of images with only a smallest cross-sectional area of the dural sac <80 mm² improved sensitivity to a range of 60 to 96 percent. SedSign could differentiate between LSS and asymptomatic controls (P = 0.004) but was not able to differentiate between LSS and LBP or between LSS and vascular claudication.

"The sign seems most sensitive in defining severe LSS cases and yet may not add any specific diagnostic information beyond the traditional history, physical examination and imaging studies that are standard in LSS diagnosis," the authors write.

Relevant financial activities outside the submitted work included expert testimony and payment for lectures.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

Diabetes, hypertension prevalent with spinal stenosis

May 07, 2013

(HealthDay)—Nonelderly, older adults with lumbar spinal stenosis (LSS) have a higher prevalence of diabetes and hypertension than those without stenosis, according to a study published in the April 20 issue ...

Fusion rate up for lumbar spinal stenosis, 2004 to 2009

Jun 13, 2013

(HealthDay)—For patients hospitalized for lumbar spinal stenosis (LSS), the rate of fusions significantly increased and the rate of decompressions significantly decreased from 2004 to 2009 in the United ...

Lumbar spinal stenosis lowers health-related QoL

Apr 07, 2012

(HealthDay) -- Patients diagnosed with lumbar spinal stenosis (LSS) have a substantial burden of illness and reduced health-related quality of life (HRQL) compared to the general population, and their HRQL ...

EP studies helpful in lumbar spinal stenosis prognosis

Dec 28, 2012

(HealthDay)—Electrophysiological abnormalities have been identified that are of some prognostic value in determining deteriorating clinical status over the long term for patients with mild-to-moderate lumbar ...

Recommended for you

Ebola mistakes should serve a lesson says WHO

18 hours ago

The World Health Organization's chief admitted on Sunday that the UN agency had been caught napping on Ebola, saying it should serve as a lesson to avoid similar mistakes in future.

British Ebola nurse discharged from hospital

Jan 25, 2015

A British nurse who contracted Ebola while working as a volunteer in Sierra Leone said she was "happy to be alive" as she was discharged from hospital on Saturday having made a full recovery.

Tide turning in Ebola fight after hard lessons

Jan 24, 2015

A top U.N. official in the fight against Ebola greeted just three patients at one treatment center he visited this week in Sierra Leone. Families in Liberia are no longer required to cremate the remains of ...

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.