Vitamin D supplementation may be beneficial in depression

April 7, 2014
Vitamin D supplementation may be beneficial in depression

(HealthDay)—Vitamin D supplementation has no overall effect on depressive symptoms, but may have a significant effect for those with clinically significant depression, according to a review published online March 14 in Psychosomatic Medicine.

Jonathan A. Shaffer, Ph.D., from the Columbia University Medical Center in New York City, and colleagues conducted a systematic review to identify randomized trials that compared the effect of vitamin D supplementation with a control condition on depression or . Seven trials, involving 3,191 participants, were included in the analyses.

The researchers found that despite considerable heterogeneity there was no overall effect for vitamin D supplementation on depressive symptoms (standardized mean difference [SMD], −0.14; P = 0.16). For participants with clinically significant depressive symptoms or , vitamin D supplementation had a moderate, statistically significant effect (two studies: SMD, −0.60; P = 0.046), while the effect was small and nonsignificant for those without clinically significant depression (five studies: SMD, −0.04; P = 0.61). The risk of bias was unclear or high in most trials.

"Vitamin D supplementation may be effective for reducing depressive symptoms in patients with clinically significant depression; however, further high quality research is needed," the authors write.

Explore further: Study finds no evidence that vitamin D supplements reduce depression

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Recommended for you

How much video gaming is too much for kids?

September 27, 2016

(HealthDay)—Playing video games might improve a child's motor skills, reaction time and even academic performance, but new research shows that too much gaming can be linked to social and behavioral problems.

How we handle objects depends on who owns them

September 27, 2016

From scissors and staplers to car keys and cell phones, we pass objects to other people every day. We often try to pass the objects so that the handle or other useful feature is facing the appropriate direction for the person ...

Dogs ignore bad advice that humans follow

September 27, 2016

Dogs are less likely to follow bad advice than children, according to a new study conducted at the Canine Cognition Center at Yale. In contrast to children, dogs only copy a human's actions if they are absolutely necessary ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.