CT-guided irreversible electroporation safe in unresectable pancreatic carcinoma

A small group of patients with locally advanced unresectable pancreatic carcinoma suffered no major ill effects—pancreatitis or fistula formation—after undergoing percutaneous CT-guided irreversible electroporation (IRE)—a nonthermal ablation technology that is safe near vascular and ductal structures—as a therapy.

"Our findings exceeded our expectations," said Maria Paola Belfiore, a researcher at the Institute of Radiology, Second University of Naples. "In fact, three patients were downstaged, and so had a greater life expectancy. This is a great new promise for inoperable tumors."

The ablation procedure was successful in 100 percent of the patients. These early results represent a good alternative to intraoperative IRE , and offer a safe and feasible primary local treatment for locally advanced pancreatic cancer.

More information: Dr. Belfiore presented the study on May 6 at the 2014 ARRS Annual Meeting in San Diego, CA.

add to favorites email to friend print save as pdf

Related Stories

Electrical pulse treatment pokes holes in hard-to-treat tumors

Apr 14, 2013

A new, minimally invasive treatment that tears microscopic holes in tumors without harming healthy tissue is a promising treatment for challenging cancers, suggests a preliminary study being presented at the Society of Interventional ...

Recommended for you

Video: Is that double mastectomy really necessary?

Oct 24, 2014

When Angeline Vuong, 27,was diagnosed with cancer in one breast earlier this year, her first reaction was "A DOUBLE MASTECTOMY. NOW. " Turns out, she's far from alone: a recent JAMA study of 190,000 breast cancer cases in ...

User comments