'Phantom' superbugs – a silent killer

June 2, 2014 by Kate Sullivan
'Phantom' superbugs – a silent killer
Researcher Hosam Mamoon Zowawi said the ‘phantom’ superbugs were found during a region-wide collaborative study on superbugs.

(Medical Xpress)—University of Queensland researchers have discovered antibiotic-resistant bacteria in the Middle East which is cloaking itself in genetic material to avoid detection and placing the population at increased risk of deadly infections.

With the Middle East an increasingly popular destination for medical tourism and international workers seeking high-paying jobs, researchers warn the hard-to-detect may quickly spread beyond the region and emerge worldwide.

Researcher Hosam Mamoon Zowawi, from the UQ Centre for Clinical Research, said the 'phantom' superbugs were found during a region-wide collaborative study on superbugs in the Gulf Cooperation Council (GCC) states of Saudi Arabia, United Arab Emirates, Kuwait, Qatar, Oman and Bahrain.

"The study found antibiotic-resistant bacteria in samples from all GCC states," Mr Zowawi said.

"Not only were the bacteria widespread, but they were found to be carrying which empowers them to resist antibiotics and avoid detection in routine laboratory testing.

"This means patients are not being treated quickly with the right antibiotics, allowing the bacteria time to spread.

"The results of this study will hopefully encourage laboratories to introduce more specific testing techniques to identify and prevent overlooking the presence of phantom superbugs.

"Implementing effective infection control precautions is also essential to minimise the spread of superbugs.

"Several clusters of the phantom superbugs were also detected in different patients from the same hospitals, suggesting patient-to-patient spread of infection is occurring," Mr Zowawi said.

The research team is now developing new diagnostic techniques to rapidly identify , including the phantom superbug.

"We hope this will help in advancing the surveillance of superbugs by reducing the turnaround time to identify the deadly ," Mr Zowawi said.

"It will also assist clinicians to apply targeted treatment and implement infection control precautions sooner."

The research findings are published in this month's Antimicrobials Agents and Chemotherapy journal.

More information: "Molecular Characterization of Carbapenemase-Producing Escherichia coli and Klebsiella pneumoniae in the Countries of the Gulf Cooperation Council: Dominance of OXA-48 and NDM Producers." Zowawi HM, et al. Antimicrob Agents Chemother. 2014 Jun;58(6):3085-3090. Epub 2014 Mar 17.

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