Amblyopia Tx at young age results in good vision later

Amblyopia tx at young age results in good vision later

(HealthDay)—Most children treated for moderate amblyopia when younger than 7 years have good visual acuity at 15 years of age, according to a study published in the July issue of JAMA Ophthalmology.

Michael X. Repka, M.D., from Johns Hopkins University in Baltimore, and colleagues randomly assigned 419 children with amblyopia (visual acuity, 20/40 to 20/100) to either patching (minimum of six hours/day) or atropine sulfate eye drops (1 percent; one drop daily), for six months. After six months, was at the discretion of the investigator. An unselected subgroup of 188 children were enrolled into long-term follow-up two years after enrollment.

The researchers found that mean visual acuity in the amblyopic eye measured at 15 years was approximately 20/25 in 147 participants; 59.9 percent of amblyopic eyes had visual acuity of 20/25 or better and 33.3 percent had visual acuity of 20/20 or better. At 15 years of age, the mean interocular acuity difference (IOD) was 2.1 lines, with 48.3 percent having an IOD of two or more lines and 71.4 percent having an IOD of one or more lines. Nine participants (aged 10 to 15 years; 6.1 percent) had prescribed treatment other than spectacles. At the 15-year examination, better visual acuity was achieved in those who were younger than 5 years at the time of entry into the , compared with those aged 5 to 6 years (P < 0.001). There were no significant differences in of amblyopic and fellow eyes at 15 years of age when comparing original treatment with atropine or patching (P = 0.44 and 0.43, respectively).

"The results indicate that improvement occurring with amblyopia treatment is maintained until at least 15 years of ," the authors write.

More information: Abstract
Full Text (subscription or payment may be required)

add to favorites email to friend print save as pdf

Related Stories

New optical metrics can identify patients on 'fast track' to decreased vision

Jun 24, 2013

Sophisticated new optical quality metrics can identify older adults likely to have more rapid age-related declines in vision, suggests a study, "Factors Accounting for the 4-Year Change in Acuity in Patients Between 50 and 80 Years", in the July issue of Optometry and Vision Science, offic ...

Recommended for you

Looking ahead: Whole eye transplant under development

Sep 22, 2014

The concept of a whole eye transplant seems futuristic, if not impossible. But with a $1million grant from the U.S. Department of Defense, researchers at University of California, San Diego School of Medicine hope to someday ...

A second look at glaucoma surgery

Sep 18, 2014

New research led by Queen's University professor Robert Campbell (Ophthalmology) has revealed using anti-inflammatory medications after glaucoma laser surgery is not helpful or necessary.

Stem cells have potential to repair diseased corneas

Sep 18, 2014

Corneal transplant (keratoplasty) is a known means of successfully treating corneal disease. However, without unlimited donor corneas, researchers say there is a need to study alternate methods of treatment ...

User comments