Bacteria found in bladders of healthy women differ from those in women with incontinence

Bacteria found in the bladders of healthy women differ from bacteria in women with a common form of incontinence, according to researchers from Loyola University Chicago Stritch School of Medicine.

These findings, published July 9, 2014, in the American Society for Microbiology's online journal mBio, suggest that bacterial communities may play a role in female urinary health.

"Urgency (UUI) is a common, yet poorly understood, condition with symptoms similar to ," said Alan Wolfe, PhD, co-investigator and professor of Microbiology and Immunology. "If we can determine that certain cause UUI symptoms, we may be able to better identify those at risk for this condition and more effectively treat them."

Approximately 15 percent of women suffer from UUI and yet an estimated 40 – 50 percent do not respond to conventional treatments. One possible explanation for the lack of response to medication may be the bacteria present in these women.

This study evaluated urine specimens of 90 women with and without UUI symptoms. Samples were collected through a catheter and analyzed using an expanded quantitative urine culture (EQUC) technique. This technique was able to find bacteria that are not identified by the standard culture techniques typically used to diagnose urinary tract syndromes. This study also used 16S rDNA sequencing to classify bacterial DNA. The UUI and non-UUI urinary bacteria differed by group based on both culture type and sequence.

"These findings may have strong implications for the prevention, diagnosis and treatment of with this form of incontinence," said Paul Schreckenberger, PhD, co-investigator and director, clinical microbiology laboratory, Loyola University Health System.

add to favorites email to friend print save as pdf

Related Stories

Bacteria in urine could contribute to overactive bladder

May 18, 2014

Contrary to popular belief, urine is not sterile and the bacteria in it may be associated with overactive bladder (OAB) in some women, according to research presented today at the annual meeting of the American ...

Study debunks common myth that urine is sterile

Apr 09, 2012

Researchers have determined that bacteria are present in the bladders of some healthy women, which discredits the common belief that normal urine is sterile. These findings were published in the April issue of the Journal of ...

Clinical review published in JAMA

Jun 06, 2014

Many women experience bothersome urine loss with laughing, coughing and sneezing (stress urinary incontinence) AND on their way to the bathroom (urge urinary incontinence). When women experience both types of urine leakage, ...

Recommended for you

Senegal monitors contacts of 1st Ebola patient

47 minutes ago

Senegalese authorities on Monday were monitoring everyone who was in contact with a student infected with Ebola who crossed into the country, and who has lost three family members to the disease.

Cerebral palsy may be hereditary

6 hours ago

Cerebral palsy is a neurological developmental disorder which follows an injury to the immature brain before, during or after birth. The resulting condition affects the child's ability to move and in some ...

19 new dengue cases in Japan, linked to Tokyo park

12 hours ago

Japan is urging local authorities to be on the lookout for further outbreaks of dengue fever, after confirming another 19 cases that were contracted at a popular local park in downtown Tokyo.

User comments