Neurologic recovery from corticospinal tract injury due to subfalcine herniation

July 25, 2014

After development of diffusion tensor tractography (DTT), which is derived from diffusion tensor imaging (DTI), three-dimensional reconstruction and estimation for three motor tracts, such as the corticospinal tract, the rubrospinal tract, and the corticoreticular pathway became possible.

The corticospinal tract is known to be a major neural tract for motor function in the human brain. Several studies have reported on injury of the corticospinal tract by transtentorial herniation. In addition, some studies have demonstrated recovery of a corticospinal tract injured by transtentorial herniation. However, very little is known about injury and recovery of the corticospinal tract related to subfalcine herniation. Researchers at College of Medicine, Yeungnam University, Republic of Korea, led by Prof. Sung Ho Jang report on a 53-year-old, male patient with subdural hematoma in the right fronto-parietal-temporal lobe and subfalcine herniation patient who showed recovery of the corticospinal tract, which was injured by the effect of a subfalcine herniation, using DTT.

The patient underwent decompressive craniectomy and removal of a hematoma at admission. At 6 weeks after onset, he was transferred to the rehabilitation department for rehabilitation. His weakness was recovered to a nearly normal state at 7 months after onset. DTT results showed that both corticospinal tracts were narrowed from the cerebral cortex to the subcorical white matter at 6 weeks after onset; however, thickenings of narrowed portions of both corticospinal tracts on 7-month DTT appear to indicate recovery of the injured corticospinal tracts. The recovery of the injured corticospinal tracts induced by subfalcine herniation may be a result of neurological remodeling under rehabilitation intervention. This article is released on the Neural Regeneration Research (Vol. 9, No. 12, 2014).

More information: Seo JP, Jang SH. Recovery of the corticospinal tracts injured by subfalcine herniation: a diffusion tensor tractography study. Neural Regen Res. 2014;9(12):1231-1233.

Related Stories

Isolating the circuits that control voluntary movement

May 7, 2014

(Medical Xpress)—Extraordinarily complex networks of circuits that transmit signals from the brain to the spinal cord control voluntary movements. Researchers have been challenged to identify the controlling circuits, but ...

Recommended for you

Take a trip through the brain (w/ Video)

July 30, 2015

A new imaging tool developed by Boston scientists could do for the brain what the telescope did for space exploration. In the first demonstration of how the technology works, published July 30 in the journal Cell, the researchers ...

Improved memory thanks to irregular sleep-wake patterns

July 31, 2015

If you've had a good night's sleep, you are mentally more alert and your memory works more reliably. During sleep, a part of our forebrain called the prefrontal cortex remains active. It ensures that memories and learned ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.