Split-dose better than day-before colonoscopy prep

Split-dose better than day-before colonoscopy prep

(HealthDay)—Split-dose regimens increase the quality of colon cleansing compared to day-before colonoscopy preparation, according to a review and meta-analysis published in the July issue of Gastroenterology.

Myriam Martel, from McGill University in Montreal, and colleagues conducted a systematic literature review to identify that assessed the efficacy of bowel cleansing for split-dose regimens versus day-before colonoscopy preparation. Studies evaluating pediatric, hospitalized, or patients were excluded.

Based on 47 trials (13,487 patients), the researchers found that split-dose preparations provided significantly better colon cleansing than day-before preparations (odds ratio [OR], 2.51). This comparison included day-before preparations with polyethylene glycol (OR, 2.60), sodium phosphate (OR, 9.34), or picosulfate (OR, 3.54). A higher proportion of were willing to repeat split-dose versus day-before cleansing (OR, 1.90), as well as low-volume split-dose preparations versus high-volume split-dose preparations (OR, 4.95). The different preparation methods did not vary with regards to side effects, complications, or outcomes of procedures.

"Additional research is required to evaluate oral sulfate solution-based and low-volume regimens further," the authors write.

One author disclosed financial ties to the medical device industry.

More information: Abstract
Full Text

Journal information: Gastroenterology

Copyright © 2015 HealthDay. All rights reserved.

Citation: Split-dose better than day-before colonoscopy prep (2015, July 6) retrieved 19 March 2024 from https://medicalxpress.com/news/2015-07-split-dose-day-before-colonoscopy-prep.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Study shows splitting bowel preparation dosage is most effective cleansing method before colonoscopy

16 shares

Feedback to editors