Saffron-based crocin prevents liver cancer

January 1, 2016
The Golden Spice is good for your liver. Credit: Bentham Science Publishers

Liver cancer remains among the leading causes of cancer-related death worldwide.

New study lead by UAE University Prof. Amr Amin unravels mechanisms by which -based 'crocin' protects against .

The study entitled 'Saffron-Based Crocin Prevents Early Lesions of Liver Cancer: In Vivo, In Vitro and Network Analyses' is funded by Al-Jalila Foundation & Terry Fox Foundation and is published in Recent Patents on Anticancer Drug Discovery.

Using murine model, human liver cancer cells, gene expression profiling and computer-assisted modeling analyses, Amin's study identifies NF-kB as a regulatory hub and a candidate therapeutic drug target for liver cancer.

Explore further: Saffron shows promise in preventing liver cancer

More information: Amr Amin et al. Saffron-Based Crocin Prevents Early Lesions of Liver Cancer: In Vivo, In Vitro and Network Analyses, Recent Patents on Anti-Cancer Drug Discovery (2015). DOI: 10.2174/1574892810666151102110248

Related Stories

Saffron shows promise in preventing liver cancer

August 22, 2011

New research suggests that saffron provides a significant chemopreventive effect against liver cancer in animal models. When saffron was administered to rats with diethylnitrosamine (DEN)-induced liver cancer an inhibition ...

A new virus in liver cancer

August 27, 2015

More than a cause of a simple infection, viruses are often involved in the development of serious diseases. Such is the case with liver cancer, which often develops in an organ that has been weakened by hepatitis B or C virus. ...

Recommended for you

1 comment

Adjust slider to filter visible comments by rank

Display comments: newest first

not rated yet Jan 02, 2016
Crete women--regardless of their relationship to the supposed Goddess--spent untold hours on their knees harvesting--Yes, you guessed it!-- saffron from crocus blossoms.

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.