Last update Antioxidant shows promise in Parkinson's disease, 21 hours ago
Diapocynin, a synthetic molecule derived from a naturally occurring compound (apocynin), has been found to protect neurobehavioral function in mice with Parkinson's Disease symptoms by preventing deficits in motor coordination. The presence of Lewy bodies in nerve cells, formed by intracellular deposits of the protein α-synuclein, is a characteristic pathologic feature of Parkinson's Disease (PD). In the quest for an animal model of PD that mimics ... Increased iron levels may be causally associated with a decreased risk of developing Parkinson's disease, says a new paper published this week in PLOS Medicine. Irene Pichler from EURAC in Italy and a group of international collea ... New research from Terry Ellis, assistant professor at Sargent College and Director of the Center for Neurorehabilitation, has found that a virtual exercise coach was effective in helping individuals with Parkinson's disease ... Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ... A large analysis of more than 100 studies from around the world shows that exposure to pesticides, or bug and weed killers, and solvents is likely associated with a higher risk of developing Parkinson's disease. The research ... In Parkinson's disease, the protein "alpha-synuclein" aggregates and accumulates within neurons. Specific areas of the brain become progressively affected as the disease develops and advances. The mechanism underlying this ... Gaucher disease causes debilitating and sometimes fatal neurodegeneration in early childhood. Recent studies have uncovered a link between the mutations responsible for Gaucher disease and an increased risk ... Parkinson's disease (PD) is a degenerative neurological disorder marked by a progressive loss of motor control. Despite intensive research, there are currently no approved therapies that have been demonstrated to alter the ... Neuroscientist Patrik Verstreken of VIB (Flanders Institute for Biotechnology) and KU Leuven has shown for the first time that dysfunctional mitochondria in brain cells can lead to learning disabilities. The link between ... McGill University researchers have unlocked a new door to developing drugs to slow the progression of Parkinson's disease. Collaborating teams led by Dr. Edward A. Fon at the Montreal Neurological Institute and Hospital -The ... New research reveals that Solanaceae—a flowering plant family with some species producing foods that are edible sources of nicotine—may provide a protective effect against Parkinson's disease. The study appearing today ... (Medical Xpress)—Researchers at the Stanford University School of Medicine have exposed the possible function, in the healthy brain, of a mysterious molecule that has been strongly implicated in Parkinson's ... A protein known to be a key player in the development of Parkinson's disease is able to enter and harm cells in the same way that viruses do, according to a Loyola University Chicago Stritch School of Medicine study. The earliest signs of Parkinson's disease can be deceptively mild. The first thing that movie star Michael J. Fox noticed was twitching of the little finger of his left hand. For years, he made light of the ... Parkinson's disease (PD) is a progressive degenerative disease affecting a person's ability to coordinate and control their muscle movement. What starts out as a tremor in a finger will eventually lead to difficulty in writing ... Parkinson's disease is a neurodegenerative disorder characterized by the death of dopamine-producing neurons in the midbrain, resulting in motor symptoms such as tremors and stiffness. The cause of cell death ... Researchers at Northeastern University in Boston have developed a gene therapy approach that may one day stop Parkinson's disease (PD) in it tracks, preventing disease progression and reversing its symptoms. The novelty of ... (Medical Xpress)—A new study could help earlier diagnosis of Parkinson's disease, after a Malaysian researcher working for Newcastle University in the UK identified that even early in the disease people experience symptoms. University of Adelaide researchers are hoping to better understand why some sufferers of Parkinson's disease experience a marked reduction in blood pressure after they've eaten a meal. In a mouse model of early Parkinson's disease (PD), animals displayed movement deficits, loss of tyrosine-hydroxylase (TH)-positive fibers in the striatum, and astro-gliosis and micro-gliosis in the substantia nigra (SN), ... (Medical Xpress)—Clumps of α-synuclein protein in nerve cells are hallmarks of many degenerative brain diseases, most notably Parkinson's disease. As part of a new initiative to speed the search for changes in the body that can help predict, diagnose, or monitor Parkinson's disease, a research team led by Pacific Northwest National Laboratory recently ... (Medical Xpress)—NorthShore University HealthSystem (NorthShore) and Mayo Clinic researchers have partnered on a study that shows genetic and clinical evidence that therapies targeting the expression of alpha-synuclein—a ... (Medical Xpress)—Researchers at the Virginia Commonwealth University Parkinson's and Movement Disorders Center have found that mitochondrial quality and functional capacity play an important role in Parkinson's ...Parkinson's & Movement disorders news
Antioxidant shows promise in Parkinson's disease
21 hours ago
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PD-like sleep and motor problems observed in alpha-synuclein mutant mice
Jun 07, 2013
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Serum iron levels may be causally associated with Parkinson's disease risk
Jun 04, 2013
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Virtual coach helps Parkinson's patients stick with exercise
May 31, 2013
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How disease mutations affect the Parkin protein
May 31, 2013
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Meta-analysis: Bug and weed killers, solvents may increase risk of Parkinson's disease
May 27, 2013
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New animal model gives insights into mechanisms of Parkinson's disease pathogenesis
May 24, 2013
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Defective cellular waste removal explains why Gaucher patients often develop Parkinson's disease
May 23, 2013
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Diabetes drug tested in Parkinson's disease patients
May 20, 2013
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Faulty energy production in brain cells leads to disorders ranging from Parkinson's to intellectual disability
May 17, 2013
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Unleashing the watchdog protein
May 09, 2013
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Could eating peppers prevent Parkinson's? Dietary nicotine may hold protective key
May 09, 2013
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Study reveals probable role of Parkinson's protein in healthy brain
May 01, 2013
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Study shows how Parkinson's disease protein acts like a virus
Apr 25, 2013
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Putting the brakes on Parkinson's: Anle138b prevents clumping of synunclein protein
Apr 23, 2013
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