Broad Institute of MIT and Harvard

Vaccination

Untangling the immune response to vaccines

The COVID-19 pandemic has turned a spotlight on the importance of vaccines, but also on key gaps in scientific understanding of how the immune system reacts to vaccines in general. Why does the immune response to some vaccines ...

Oncology & Cancer

Immune cell 'hubs' discovered hiding in tumors

A tumor in the human body is like a city at war, bustling with cancer cells, immune cells, blood vessels, signaling molecules and surrounding tissue. A simple census of these players will provide some basic information on ...

Oncology & Cancer

What makes some immune cells better at killing melanoma

T cells rely on surface proteins called T cell receptors (TCRs) to bind to and destroy viruses, cancer cells, and other invaders in the body. T cells that infiltrate tumors, however, can have varied, sometimes ineffective ...

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