Thyroid cancer is the most common type of endocrine cancer in children. Because it is bilateral—affecting both sides (lobes) of the thyroid—in more than one third of pediatric patients, initial treatment typically involves ...
Mar 1, 2022
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Gene therapy trials for sickle cell disease have been showing great promise, even offering hope of a cure. But in early 2021, the trials ground to a halt after reports of blood malignancies in two people in a trial sponsored ...
Feb 15, 2022
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What happens in our respiratory tract once we're exposed to COVID-19? A three-dimensional airway model, made from patient-derived stem cells, could provide answers about the initial stages of infection. The model not only ...
Feb 9, 2022
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Enteroendocrine cells punch above their weight. Constituting just about 1 percent of intestinal cells, they produce, as a group, around 15 different hormones. These not only regulate intestinal function and digestion, but ...
Feb 9, 2022
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We now know that the microbes that live in our intestines—our microbiome—influence our health in many ways. The balance among competing microbial species is believed to be important in inflammatory bowel disease (IBD), ...
Feb 3, 2022
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A central feature of type 1 diabetes is loss of the pancreatic beta cells that make insulin. Researchers led by Paolo Fiorina, MD, Ph.D., of Boston Children's Hospital and Francesca D'Addio, MD, of the University of Milan ...
Feb 3, 2022
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Pain-predominant disorders of gut-brain interaction (DGBIs) in children—such as functional abdominal pain (FAP) and irritable bowel syndrome (IBS)— can lead to disabling symptoms, poor quality of life and high use of ...
Jan 31, 2022
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The need for mental health care in children and adolescents has been surging; rates of suicide and self-harm are increasing, and, like hospitals, primary care practices are struggling with an influx of patients. Properly ...
Jan 25, 2022
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Cerebral palsy, a non-progressing motor impairment that begins in early childhood, has widely been viewed as the result of oxygen deprivation during birth or other birth-related factors such as prematurity. While this is ...
Jan 25, 2022
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Current messenger RNA vaccines appear to offer at least some protection against new SARS-CoV-2 variants, including omicron, especially for people who have received boosters. But manufacturing costs and the need for ultra-cold ...
Jan 20, 2022
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