Cold Spring Harbor Laboratory
Rats take high-speed multisensory snapshots
When animals are on the hunt for food they likely use many senses, and scientists have wondered how the different senses work together. New research from the laboratory of CSHL neuroscientist and Assistant Professor Adam ...
Neuroscience
May 07, 2013 |
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Scientists discover how brain's auditory center transmits information for decisions, actions
When a pedestrian hears the screech of a car's brakes, she has to decide whether, and if so, how, to move in response. Is the action taking place blocks away, or 20 feet to the left?
Neuroscience
May 01, 2013 |
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New evidence for genetic basis of autism found
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered that one of the most common genetic alterations in autism -- deletion of a 27-gene cluster on chromosome 16 -- causes autism-like features. ...
Genetics
Oct 03, 2011 |
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Study solves birth and migration mysteries of cortex's powerful inhibitors, 'chandelier' cells
A team at CSHL for the 1st time reveals the birth timing and embryonic origin of a critical class of inhibitory brain cells called chandelier cells, tracing the specific paths they take during early development into the cerebral ...
Neuroscience
Nov 22, 2012 |
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Neuroscientists pinpoint location of fear memory in amygdala
A rustle of undergrowth in the outback: it's a sound that might make an animal or person stop sharply and be still, in the anticipation of a predator. That "freezing" is part of the fear response, a reaction to a stimulus ...
Neuroscience
Jan 28, 2013 |
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Scientists reverse Alzheimer's-like memory loss in animal models by blocking EGFR signaling
A team of neuroscientists and chemists from the U.S. and China today publish research suggesting that a class of currently used anti-cancer drugs as well as several previously untested synthetic compounds show effectiveness ...
Alzheimer's disease & dementia
Sep 24, 2012 |
4.8 / 5 (4) |
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New automated imaging to greatly speed whole-brain mapping efforts
A new technology developed by neuroscientists at Cold Spring Harbor Laboratory (CSHL) transforms the way highly detailed anatomical images can be made of whole brains. Until now, means of obtaining such images ...
Medical research
Jan 15, 2012 |
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Gene mutation in autism found to cause hyperconnectivity in brain's hearing center
New research from Cold Spring Harbor Laboratory (CSHL) might help explain how a gene mutation found in some autistic individuals leads to difficulties in processing auditory cues and paying spatial attention to sound.
Neuroscience
Jan 31, 2012 |
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ENCODE project: In massive genome analysis new data suggests 'gene' redefinition
Most people understand genes to be specific segments of DNA that determine traits or diseases that are inherited. Textbooks suggest that genes are copied ("transcribed") into RNA molecules, which are then used as templates ...
Genetics
Sep 05, 2012 |
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Neuroscientists show 'jumping genes' may contribute to aging-related brain defects
As the body ages, the physical effects are notable; wrinkles in the skin appear, physical exertion becomes harder. But there are also less visible processes going on. Inside aging brains there is another phenomenon at work, ...
Neuroscience
Apr 08, 2013 |
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Researchers identify new strategy for interfering with potent cancer-causing gene
Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible ...
Cancer
Feb 11, 2013 |
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Neuroscientists propose revolutionary DNA-based approach to map wiring of whole brain
A team of neuroscientists has proposed a new and potentially revolutionary way of obtaining a neuronal connectivity map (the "connectome") of the whole brain of the mouse. The details are set forth in an essay published October ...
Neuroscience
Oct 23, 2012 |
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Team finds mechanism of one of the most powerful tumor-suppressor proteins, Chd5
A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects.
Cancer
Jan 10, 2013 |
4.5 / 5 (6) |
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Research identifies protein that regulates key 'fate' decision in cortical progenitor cells
Researchers at Cold Spring Harbor Laboratory (CSHL) have solved an important piece of one of neuroscience's outstanding puzzles: how progenitor cells in the developing mammalian brain reproduce themselves while also giving ...
Neuroscience
Sep 21, 2012 |
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Rats match humans in decision-making that involves combining different sensory cues: study
The next time you set a trap for that rat running around in your basement, here's something to consider: you are going up against an opponent whose ability to assess the situation and make decisions is statistically ...
Neuroscience
Mar 13, 2012 |
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