Dana-Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved ...
Feb 8, 2013
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Black men diagnosed with prostate cancer classified as low risk may actually have a more-aggressive form of the disease that is more likely to be fatal than in nonblack men placed in the same prognostic category, a new study ...
Dec 18, 2018
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Advancing the understanding of synovial sarcoma, a highly aggressive and rare cancer of young people, scientists at Dana-Farber Cancer Institute have discovered how an abnormal protein misdirects and disrupts the control ...
Aug 3, 2020
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In people with chronic infections or cancer, disease-fighting T cells tend to behave like an overworked militia - wheezing, ill-prepared, tentative - in a state of "exhaustion" that allows disease to persist. In a paper posted ...
Oct 27, 2016
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Researchers reported promising preliminary outcomes for the first four children enrolled in a U.S. gene therapy trial for Wiskott-Aldrich syndrome (WAS), a life-threatening genetic blood and immune disorder, at the 57th annual ...
Dec 6, 2015
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Bone marrow biopsies are the gold standard for diagnosing and monitoring the progression of multiple myeloma, but these procedures are far too invasive to perform at every patient visit. Scientists from the Dana-Farber Cancer ...
Apr 27, 2018
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Researchers led by scientists at Dana-Farber Cancer Institute say they have identified unique genomic changes that may be integral to testicular cancer development and explain why the great majority are highly curable with ...
Nov 30, 2016
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A new form of gene therapy for boys with X-linked severe combined immunodeficiency syndrome (SCID-X1), a life-threatening condition also known as "bubble boy" disease, appears to be both effective and safe, according to a ...
Oct 8, 2014
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A novel agent that targets a mutated form of the KRAS gene—the most commonly altered oncogene in human cancers and one long considered "undruggable"—shrank tumors in most patients in a clinical trial with manageable side ...
Oct 25, 2020
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Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumors, which so far have resisted the ground-breaking cancer treatment based on harnessing the body's immune system. The discovery, ...
Feb 15, 2021
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