Harvard University

Oncology & Cancer

Moving the needle on monitoring skin cancer

Patients with melanoma, the most concerning form of skin cancer in which pigment-producing cells start to grow out of control, can benefit from existing immunotherapies, but by far not all of them do. More than 50% of patients ...

Immunology

Tuning T cell traits and functions with biomechanical materials

The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the same patient, especially against ...

Diseases, Conditions, Syndromes

A 'backpack' full of multiple sclerosis therapy

Multiple sclerosis (MS) is a devastating autoimmune disease that destroys the protective myelin covering around nerves, disrupting communication between the brain and body, and causing patients' ability to move and function ...

Medical research

New approach to slowing aggressive leukemia

A team of Harvard and Sloan Kettering scientists has developed compounds that can target and degrade proteins associated with acute myeloid leukemia (AML) and nearly doubled the life expectancy of mice with cancer in laboratory ...

Gerontology & Geriatrics

Clearing a path for non-invasive muscle therapy for the elderly

Mechanotherapy, the concept of using mechanical forces to stimulate tissue healing, has been used for decades as a form of physical therapy to help heal injured muscles. However, the biological basis and optimal settings ...

Oncology & Cancer

CAR-T cell cancer immunotherapy gets personal

New adoptive T cell therapies—in which T cells, the immune system's natural hunters patrolling the body for foreign adversaries, are retrieved from cancer-riddled patients, super-charged and amplified outside the body, ...

Oncology & Cancer

Enhanced cancer immunotherapies through cytokine-labeled T cells

The recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the ...

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