Helmholtz Association of German Research Centres

Neuroblastoma: Autophagy protects from chemotherapy

Neuroblastomas are pediatric tumors that originate from cells of the embryonic nervous system. The disease can take widely varying clinical courses that range from spontaneous regression to fatal outcomes. Highly aggressive ...

Jul 01, 2013
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A circuitous route to therapy resistance

Gliomas are malignant brain tumors that arise from glial cells called astrocytes, found in the central nervous system. "In treating malignant gliomas, we currently combine radiotherapy with the anticancer drug temozolomide. ...

Jun 26, 2013
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No danger of cancer through gene therapy virus

In fall 2012, the European Medicines Agency (EMA) approved the modified adeno-associated virus AAV-LPL S447X as the first ever gene therapy for clinical use in the Western world. uniQure, a Dutch biotech company, had developed ...

Jun 19, 2013
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Colon cancer screening: Immunological tests are superior

Tests for hidden traces of blood ("occult blood") in the stool provide clues to colon cancer or precancerous lesions. For over 40 years, an enzymatic detection method has been used to detect the diseases. Now immunological ...

May 28, 2013
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Individual efficacy of chemotherapies

The function of the mitochondria – also defined as "power plants" within the cells – is essential as to whether, and how, some chemotherapeutic agents take effect in tissue. Scientists at the Helmholtz ...

May 10, 2013
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How the brain folds to fit

During fetal development of the mammalian brain, the cerebral cortex undergoes a marked expansion in surface area in some species, which is accommodated by folding of the tissue in species with most expanded ...

Apr 26, 2013
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