Helmholtz Association of German Research Centres
Researchers show long-term consequences of chronic virus infection
The cytomegalovirus (CMV) is a member of the herpesvirus family. Although most people carry CMV for life, it hardly ever makes them sick. Researchers from the Helmholtz Centre for Infection Research and from ...
Diseases, Conditions, Syndromes
Aug 16, 2012 |
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New key element discovered in pathogenesis of Burkitt lymphoma
Burkitt lymphoma is a malignant, fast-growing tumor that originates from a subtype of white blood cells called B lymphocytes of the immune system and often affects internal organs and the central nervous system. Now Dr. Sandrine ...
Cancer
Aug 13, 2012 |
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Researchers develop new approach to treat acute liver failure
Acute liver failure is a life-threatening disease, characterized by a sudden, massive death of liver cells. Unfortunately, few treatment options exist, especially for advanced-stage liver failure. As a last resort a liver ...
Diseases, Conditions, Syndromes
Aug 03, 2012 |
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Autoantibodies damage blood vessels in the brain -- important factor in development of dementia
The presence of specific autoantibodies of the immune system is associated with blood vessel damage in the brain. These findings were made by Marion Bimmler, a graduate engineer of medical laboratory diagnostics ...
Neuroscience
Jul 31, 2012 |
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Genome analysis of brain tumors showing the way to new treatment strategies
Brain tumors are the primary cause of cancer mortality in children. Even if a cure is possible, young patients often suffer from the stressful treatment which can be harmful to the developing brain. The most common childhood ...
Cancer
Jul 26, 2012 |
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Neural precursor cells induce cell death in certain brain tumors
Neural precursor cells (NPC) in the young brain suppress certain brain tumors such as high-grade gliomas, especially glioblastoma (GBM), which are among the most common and most aggressive tumors. Now researchers of the Max ...
Cancer
Jul 23, 2012 |
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Dual effect on tumor blood vessels
Angiogenesis is considered to be a major target of new cancer treatments. Angiopoietin-2 (Ang-2) is one of the key regulators of angiogenesis. Scientists of the German Cancer Research Center and Medical Faculty Mannheim, ...
Cancer
May 31, 2012 |
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MicroRNA controls malignancy and resistance of breast cancer cells
Many breast cancer patients are treated with a drug called tamoxifen. The substance blocks the effect of estrogen and thus suppresses the growth signals of this hormone in cancer cells. When resistance to the drug develops, ...
Cancer
May 04, 2012 |
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Gene mutation leads to impairment of 2 senses: Touch and hearing
People with good hearing also have a keen sense of touch; people with impaired hearing generally have an impaired sense of touch. Extensive data supporting this hypothesis was presented by Dr. Henning Frenzel and Professor ...
Genetics
May 01, 2012 |
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Death cap mushroom poison to arrest pancreatic cancer in mice
The mere thought of an identification error sends a chill down the spine of any mushroom lover: The death cap mushroom (Amanita phalloides), which resembles the common white button mushroom, contains one of the most deadly ...
Cancer
Apr 02, 2012 |
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Scientists elucidate molecular mechanism contributing to cardiomyopathy
Cardiomyopathy comprises a deterioration of the heart muscle that affects the organ's ability to efficiently pump blood through the body. Previously researchers have tied forms of the disease to the alternative splicing of ...
Cardiology
Apr 01, 2012 |
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The molecular basis of touch sensation: New function of a well-known gene identified
A gene known to control lens development in mice and humans is also crucial for the development of neurons responsible for mechanosensory function, as neurobiologists of the Max Delbrück Center for Molecular Medicine ...
Genetics
Feb 21, 2012 |
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Research reveals molecular mechanism underlying severe anomalies of the forebrain
Researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch have now identified and described a molecular mechanism underlying the most common malformation of the brain in humans. In holoprosencephaly ...
Medical research
Feb 14, 2012 |
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Stress in cells activates hepatitis viruses
People who have received a donor organ need lifelong immunosuppressant drugs to keep their immune system from attacking the foreign tissue. However, with a suppressed immune system, many infectious agents ...
Medical research
Feb 13, 2012 |
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Defects in the packaging of DNA in malignant brain tumors
Glioblastomas grow extremely aggressively into healthy brain tissue and, moreover, are highly resistant to radiation therapy and chemotherapy. Therefore, they are regarded as the most malignant type of brain tumor. Currently ...
Cancer
Jan 30, 2012 |
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