Ludwig Institute for Cancer Research

The Ludwig Institute for Cancer Research Ltd (LICR) is a global non-profit medical research institute that undertakes laboratory and clinical research into cancer, conducting and sponsoring its own early-phase clinical trials to investigate its discoveries. LICR is the largest international, non-profit institute dedicated to understanding and controlling cancer, with ~900 staff in seven countries across Australasia, Europe, and North and South America. There are currently nine LICR research Branches, which have a primary focus on basic laboratory and translational (in vivo and preclinical analyses of laboratory discoveries) sciences and are typically located within a university or research institute.

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The STING of radiation

A team of researchers led by Ludwig Chicago's Yang-Xin Fu and Ralph Weichselbaum has uncovered the primary signaling mechanisms and cellular interactions that drive immune responses against tumors treated with radiotherapy. ...

Nov 20, 2014
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Targeting cancer's sweet tooth

Ludwig researchers have elucidated a key mechanism by which cancer cells change how they metabolize glucose to generate the energy and raw materials required to sustain runaway growth.

Oct 21, 2013
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Herding cancer cells to their death

An advanced tumor is a complex ecosystem. Though derived from a single cell, it evolves as it grows until it contains several subspecies of cells that vary dramatically in their genetic traits and behaviors. This cellular ...

Jun 20, 2013
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Mapping the embryonic epigenome

A large, multi-institutional research team involved in the NIH Epigenome Roadmap Project has published a sweeping analysis in the current issue of the journal Cell of how genes are turned on and off to direct early human ...

May 09, 2013
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A hijacking of healthy cellular circuits

Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor (EGFR), ...

Apr 08, 2013
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