St. Jude Children's Research Hospital

St. Jude Children's Research Hospital, founded in 1962, is a leading pediatric treatment and research facility focused on children's catastrophic diseases. It is located in Memphis, Tennessee, and is a nonprofit medical corporation.


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T cells rely on 'rheostat' to help ensure that the immune response matches the threat

A properly functioning immune system is a lesson in balance, providing protection against disease without attacking healthy tissue. Work led by St. Jude Children's Research Hospital scientists and published recently in Nature Im ...

Immunology created Apr 30, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Whole genome sequencing finds new mutations to blame for a majority of brain tumor subtype

Washington University Pediatric Cancer Genome Project has identified mutations responsible for more than half of a subtype of childhood brain tumor that takes a high toll on patients. Researchers also found evidence the tumors ...

Genetics created Apr 14, 2013 | popularity not rated yet | comments 0 | with audio podcast

Cancer drug shortages mean higher costs and greater risk for patients

A national survey of health professionals showed that drug shortages are taking a heavy toll on cancer patients, forcing treatment changes and delays that for some patients meant worse outcomes, more therapy-related complications ...

Cancer created Mar 21, 2013 | popularity not rated yet | comments 0

Inherited genetic variations have a major impact on childhood leukemia risk

Humans have between 20,000 and 25,000 genes that carry instructions for assembling the proteins that do the work of cells. Work led by St. Jude Children's Research Hospital found that children who inherit certain variations ...

Cancer created Mar 19, 2013 | popularity not rated yet | comments 0 | with audio podcast

Two new genes linked to amyotrophic lateral sclerosis and related disorders

(Medical Xpress)—A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, ...

Genetics created Mar 18, 2013 | popularity not rated yet | comments 0 | with audio podcast

Rise in drug costs to hospitals, clinics slowing in 2013

Even though costs for medications will continue to rise in 2013 by as much as 4 percent, the increase is projected to be less than in previous years, according to a report in the advance online publication of the American Jo ...

Medications created Feb 18, 2013 | popularity not rated yet | comments 0

Gene sequencing project mines data once considered 'junk' for clues about cancer

Genome sequencing data once regarded as junk is now being used to gain important clues to help understand disease. The latest example comes from the St. Jude Children's Research Hospital – Washington University Pediatric ...

Cancer created Jan 24, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study finds new genetic defects in high-risk childhood leukemia subtypes with chromosomal loss

Research led by St. Jude Children's Research Hospital scientists has identified a possible lead in treatment of two childhood leukemia subtypes known for their dramatic loss of chromosomes and poor treatment outcomes.

Genetics created Jan 20, 2013 | popularity not rated yet | comments 0 | with audio podcast

Gene sequencing project identifies abnormal gene that launches rare childhood leukemia

Research led by the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project has identified a fusion gene responsible for almost 30 percent of a rare subtype of childhood leukemia with ...

Cancer created Nov 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

Legacy bead program helps children and their families cope with life-threatening illnesses

When Kayla Dehnert tells friends and family in Northern California about life as a St. Jude Children's Research Hospital patient, she pulls out a string of beads taller than she is.

Health created Sep 17, 2012 | popularity not rated yet | comments 0

Improved diagnostic test benefits children with acute myeloid leukemia

Early treatment response is a powerful predictor of long-term outcome for young patients with acute myeloid leukemia (AML). The information can help physicians decide whether a more intensive approach is needed. Research ...

Cancer created Sep 10, 2012 | popularity not rated yet | comments 0

Intervention helps children with sickle cell disease complete MRI tests without sedation

Sitting still is tough for children, which makes MRI scans a challenge. The scans require that patients remain motionless for extended periods. Findings from St. Jude Children's Research Hospital showed that ...

Pediatrics created Aug 31, 2012 | popularity not rated yet | comments 0

Existing drugs offer new treatment options for high-risk childhood leukemia subtype

Scientists have identified new genetic alterations underlying a high-risk subtype of the most common childhood cancer that could be effectively targeted with existing leukemia therapies.

Cancer created Aug 13, 2012 | popularity not rated yet | comments 0 | with audio podcast

New regulatory mechanism discovered in cell system for eliminating unneeded proteins

A faulty gene linked to a rare blood vessel disorder has led investigators to discover a mechanism involved in determining the fate of possibly thousands of proteins working inside cells.

Medical research created Aug 10, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Target for potent first-strike influenza drugs identified

(Medical Xpress) -- Scientists at St. Jude Children’s Research Hospital have reported details of how certain drugs can precisely target and inhibit an enzyme essential for the influenza virus’ replication. Since ...

Medical research created Aug 03, 2012 | popularity not rated yet | comments 0