The Scripps Research Institute
The Scripps Research Institute (TSRI) is a biomedical research corporation established in La Jolla, California with another site in Jupiter, Florida. Its origins stem from a large endowment from Ellen Browning Scripps in the 1920s originally targeted for research on immune disorders. In the 1990s the combined Scripps Clinic and Research Institute became separate entitities. Today, TSRI is one of the most prolific and active research institutes in the United States with a wide range of human disorders/conditions in its focus. Namely, cancer biology, cell therapy, genetics, molecular and experimental medicine, neurobiology and more. The newly constructed Scripps Florida focuses on drug discoveries, basic biomedical research and technologies.
Heroin vaccine blocks relapse in preclinical study
Scientists at The Scripps Research Institute (TSRI) have reported successful preclinical tests of a new vaccine against heroin. The vaccine targets heroin and its psychoactive breakdown products in the bloodstream, preventing ...
Medical research
May 06, 2013 |
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Team finds dissimilar proteins evolved similar 7-part shape
Solving the structure of a critical human molecule involved in cancer, scientists at The Scripps Research Institute (TSRI) have found what they call a good example of structural conservation—dissimilar ...
Medical research
May 01, 2013 |
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Scientists create novel approach to find RNAs involved in long-term memory storage
(Phys.org) —Despite decades of research, relatively little is known about the identity of RNA molecules that are transported as part of the molecular process underpinning learning and memory. Now, working together, scientists ...
Medical research
Apr 25, 2013 |
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Team finds antibody that transforms bone marrow stem cells directly into brain cells
In a serendipitous discovery, scientists at The Scripps Research Institute (TSRI) have found a way to turn bone marrow stem cells directly into brain cells.
Medical research
Apr 22, 2013 |
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Study finds interferon, one of the body's proteins, induces persistent viral infection
Scientists at The Scripps Research Institute (TSRI) have made a counterintuitive finding that may lead to new ways to clear persistent infection that is the hallmark of such diseases as AIDS, hepatitis B and hepatitis C.
Medical research
Apr 11, 2013 |
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Study unravels central mystery of Alzheimer's disease
Scientists at The Scripps Research Institute (TSRI) have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the Alzheimer's process and how ...
Neuroscience
Apr 10, 2013 |
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Scientists identify first potentially effective therapy for human prion disease
Human diseases caused by misfolded proteins known as prions are some of most rare yet terrifying on the planet—incurable with disturbing symptoms that include dementia, personality shifts, hallucinations ...
Medical research
Apr 03, 2013 |
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New vaccine-design approach targets HIV and other fast-mutating viruses
A team led by scientists from The Scripps Research Institute (TSRI) and the International AIDS Vaccine Initiative (IAVI) has unveiled a new technique for vaccine design that could be particularly useful against ...
HIV & AIDS
Mar 28, 2013 |
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Study reveals how serotonin receptors can shape drug effects from LSD to migraine medication
A team including scientists from The Scripps Research Institute (TSRI), the University of North Carolina at Chapel Hill and the Chinese Academy of Sciences has determined and analyzed the high-resolution ...
Medical research
Mar 21, 2013 |
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Study underlines potential of new technology to diagnose disease
Researchers at The Scripps Research Institute (TSRI) in Jupiter, FL, have developed cutting-edge technology that can successfully screen human blood for disease markers. This tool may hold the key to better diagnosing and ...
Medical research
Mar 21, 2013 |
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Study discloses new test for river blindness infection
Scientists at The Scripps Research Institute (TSRI) have found a telltale molecular marker for Onchocerciasis or "river blindness," a parasitic infection that affects tens of millions of people in Africa, ...
Diseases, Conditions, Syndromes
Feb 25, 2013 |
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Scientists find promising new approach to preventing progression of breast cancer
February 15, 2013 – Doctors currently struggle to determine whether a breast tumor is likely to shift into an aggressive, life-threatening mode—an issue with profound implications for treatment. Now a group from The Scripps ...
Cancer
Feb 15, 2013 |
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Compound developed by scientists protects heart cells during and after attack
Using two different compounds they developed, scientists from the Florida campus of The Scripps Research Institute (TSRI) have been able to show in animal models that inhibiting a specific enzyme protects heart cells and ...
Cardiology
Feb 07, 2013 |
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How chromosomes keep their loose ends loose
We take it for granted that our chromosomes won't stick together, yet this kind of cellular disaster would happen constantly were it not for a protein called TRF2. Now, scientists at The Scripps Research Institute (TSRI) ...
Medical research
Feb 06, 2013 |
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Scientists find key element of lupus, suggesting better drug targets
A team led by scientists at The Scripps Research Institute (TSRI) has identified specific cellular events that appear key to lupus, a debilitating autoimmune disease that afflicts tens of millions of people worldwide. The ...
Medical research
Feb 04, 2013 |
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