Thomas Jefferson University
Researchers capture major chemotherapeutic target in complex with DNA damage
A new study published in Science May 11 is shedding light on the molecular details of PARP-1, a DNA damage-detecting enzyme that when inhibited has been shown to be effective in fighting cancer and other ...
Medical research
May 10, 2012 |
4.7 / 5 (3) |
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Poorer quality of life for gay men and minorities after prostate cancer treatment: What are we missing?
To improve the quality of life in gay men and minorities treated for prostate cancer, a greater awareness of ethnic and sexual preference-related factors is needed to help men choose a more-suitable treatment plan, researchers ...
Cancer
Apr 30, 2012 |
5 / 5 (1) |
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Eliminating the 'good cholesterol' receptor may fight breast cancer
Removing a lipoprotein receptor known as SR-BI may help protect against breast cancer, as suggested by new findings presented at the American Association for Cancer Research Annual Meeting 2012 by Jefferson's Kimmel Cancer ...
Cancer
Apr 03, 2012 |
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New biomarker to identify hepatitis B-infected patients at risk for liver cancer
Hepatitis B-infected patients with significantly longer telomeres — the caps on the end of chromosomes that protect our genetic data — were found to have an increased risk of getting liver cancer compared to those ...
Cancer
Apr 03, 2012 |
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Carotid artery stenting found to be safe in the elderly
Researchers at Thomas Jefferson University Hospital in Philadelphia and a multicenter team of investigators have found that carotid artery stenting (CAS) is safe and effective in patients age 70 and older.
Cardiology
Mar 26, 2012 |
4 / 5 (1) |
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Tears during coronary angioplasty: Where are they and how do they affect patient outcomes?
Researchers from Thomas Jefferson University Hospital discovered that blockages in the right coronary artery and those in bending areas of the coronary artery are the most common places for dissection, a tear in the artery ...
Cardiology
Mar 24, 2012 |
5 / 5 (1) |
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Cancer paradigm shift: Biomarker links clinical outcome with new model of lethal tumor metabolism
Researchers at the Kimmel Cancer Center at Jefferson have demonstrated for the first time that the metabolic biomarker MCT4 directly links clinical outcomes with a new model of tumor metabolism that has patients "feeding" ...
Cancer
Mar 15, 2012 |
5 / 5 (3) |
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Surgery less than 24 hours after traumatic cervical spinal cord injury leads to improved outcomes
Researchers at the Rothman Institute at Jefferson have shown that patients who receive surgery less than 24 hours after a traumatic cervical spine injury suffer less neural tissue destruction and improved clinical outcomes. ...
Surgery
Mar 06, 2012 |
5 / 5 (1) |
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Stronger intestinal barrier may prevent cancer in the rest of the body, new study suggests
A leaky gut may be the root of some cancers forming in the rest of the body, a new study published online Feb. 21 in PLoS ONE by Thomas Jefferson University researchers suggests.
Immunology
Feb 21, 2012 |
5 / 5 (1) |
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Curry spice component may help slow prostate tumor growth
Curcumin, an active component of the Indian curry spice turmeric, may help slow down tumor growth in castration-resistant prostate cancer patients on androgen deprivation therapy (ADT), a study from researchers ...
Cancer
Feb 10, 2012 |
4.5 / 5 (10) |
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Researchers show benefits of local anesthesia after knee replacement surgery
Researchers at the Rothman Institute at Jefferson have shown that local anesthesia delivered through a catheter in the joint, intraarticularly, may be more beneficial than traditional opioids such as morphine and Oxycontin ...
Surgery
Feb 10, 2012 |
4 / 5 (1) |
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Rothman at Jefferson research suggests abandon convention in diagnosing periprosthetic joint infection
In their search for new, better ways to diagnose periprosthetic joint infection, Rothman Institute at Jefferson researchers have discovered that measurement of C-reactive protein in the synovial fluid is extremely accurate, ...
Diseases, Conditions, Syndromes
Feb 08, 2012 |
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Researchers find epidural steroid injections do not benefit spine patients
Researchers at the Rothman Institute at Jefferson examined data on patients being treated for lumbar stenosis and the degenerative spine condition spondylolisthesis and found that patients who received epidural steroid injections ...
Other
Feb 07, 2012 |
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Research suggests use of LE strips to diagnose PJI
Rothman Institute at Jefferson joint researchers continue to seek better ways to diagnose and subsequently treat periprosthetic joint infection (PJI) in patients following total joint arthroplasty. Their latest research shows ...
Diseases, Conditions, Syndromes
Feb 07, 2012 |
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Drugs targeting chromosomal instability may fight a particular breast cancer subtype
Another layer in breast cancer genetics has been peeled back. A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of ...
Cancer
Feb 06, 2012 |
5 / 5 (1) |
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