Thomas Jefferson University

Conspicuous tRNA lookalikes riddle the human genome

Transfer RNAs (tRNAs) are ancient workhorse molecules and part of the cellular process that creates the proteins, critical building blocks of life that keep a cell running smoothly. A new discovery suggests ...

Oct 08, 2014
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Hormone loss could be involved in colon cancer

Some cancers, like breast and prostate cancer, are driven by hormones such as estrogen and testosterone, but to date, there are none that are driven by the lack of a hormone. New evidence suggests that human colon cells may ...

Oct 10, 2014
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Gobbling up poison: A method for killing colon cancer

These days, cancer researchers aim to design targeted and specific therapy – those that kill cancer but spare the surrounding tissue. Immunotoxins, which use cancer-targeted antibodies linked to deadly ...

Sep 08, 2014
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Can antibiotics cause autoimmunity?

The code for every gene includes a message at the end of it that signals the translation machinery to stop. Some diseases, such as cystic fibrosis and Duchenne muscular dystrophy, can result from mutations that insert this ...

Mar 31, 2014
popularity 3.5 / 5 (2) | comments 0

Cyclin D1 governs microRNA processing in breast cancer

Cyclin D1, a protein that helps push a replicating cell through the cell cycle also mediates the processing and generation of mature microRNA (miRNA), according to new research publishing November 29 in Nature Communications. The re ...

Nov 29, 2013
popularity 5 / 5 (2) | comments 0 | with audio podcast