Thomas Jefferson University

Amplification of a Stat5 gene produces excess oncogenic protein that drives prostate cancer spread

An international group of investigators, led by researchers at Thomas Jefferson University's Kimmel Cancer Center, have solved the mystery of why a substantial percentage of castrate-resistant metastatic prostate cancer cells ...

Cancer created May 07, 2013 | popularity not rated yet | comments 0

VEGF may not be relevant biomarker for advanced prostate cancer

The well-studied protein VEGF does not appear to have any prognostic or predictive value for men with locally advanced prostate cancer, researchers from the Department of Radiation Oncology at Thomas Jefferson University ...

Cancer created Apr 29, 2013 | popularity not rated yet | comments 0

Curry spice component may help slow prostate tumor growth

Curcumin, an active component of the Indian curry spice turmeric, may help slow down tumor growth in castration-resistant prostate cancer patients on androgen deprivation therapy (ADT), a study from researchers ...

Cancer created Feb 10, 2012 | popularity 4.5 / 5 (10) | comments 0 | with audio podcast

Researchers capture major chemotherapeutic target in complex with DNA damage

A new study published in Science May 11 is shedding light on the molecular details of PARP-1, a DNA damage-detecting enzyme that when inhibited has been shown to be effective in fighting cancer and other ...

Medical research created May 10, 2012 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Brazilian mediums shed light on brain activity during a trance state

Researchers at Thomas Jefferson University and the University of Sao Paulo in Brazil analyzed the cerebral blood flow (CBF) of Brazilian mediums during the practice of psychography, described as a form of writing whereby ...

Neuroscience created Nov 16, 2012 | popularity 4.3 / 5 (13) | comments 2 | with audio podcast

Single vaccines to protect against both rabies and Ebola

Researchers from Thomas Jefferson University, among other institutions, including the National Institute of Allergy and Infectious Diseases, have developed single vaccines to protest against both rabies and ...

Medical research created Aug 25, 2011 | popularity 5 / 5 (4) | comments 1 | with audio podcast

Researchers mirror human response to bacterial infection and resolution in mice

Imitating human diseases using an animal model is a difficult task, but Thomas Jefferson University researchers have managed to come very close.

Medical research created Dec 14, 2011 | popularity not rated yet | comments 0 | with audio podcast

Physician's empathy directly associated with positive clinical outcomes, confirms large study

Patients of doctors who are more empathic have better outcomes and fewer complications, concludes a large, empirical study by a team of Thomas Jefferson University and Italian researchers who evaluated relationships between ...

Health created Sep 10, 2012 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Stronger intestinal barrier may prevent cancer in the rest of the body, new study suggests

A leaky gut may be the root of some cancers forming in the rest of the body, a new study published online Feb. 21 in PLoS ONE by Thomas Jefferson University researchers suggests.

Immunology created Feb 21, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Brachytherapy reduced death rates in high-risk prostate cancer patients, study finds

Brachytherapy for high-risk prostate cancers patients has historically been considered a less effective modality, but a new study from radiation oncologists at the Kimmel Cancer Center at Jefferson suggests otherwise. A population-based ...

Cancer created Jan 25, 2012 | popularity 4 / 5 (1) | comments 0

Loss of protective heart failure protein linked to critical limb ischemia

Restoring diminished levels of a protein shown to prevent and reverse heart failure damage could also have therapeutic applications for patients with critical limb ischemia (CLI), suggests a new preclinical study published ...

Medical research created Oct 10, 2012 | popularity not rated yet | comments 0 | with audio podcast

Drugs targeting chromosomal instability may fight a particular breast cancer subtype

Another layer in breast cancer genetics has been peeled back. A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD., FACP, Director of the KCC and Chair of the Department of ...

Cancer created Feb 06, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Allergy to Plavix can be overcome: study

Allergies to Plavix, also know by its chemical name, Clopidogrel occur in about six percent of patients given the drug, vital for the prevention of life-threatening stent thrombosis after angioplasty and percutaneous coronary ...

Medications created Jan 16, 2012 | popularity not rated yet | comments 0

Tissue around tumor holds key to fighting triple negative breast cancer

A natural substance found in the surrounding tissue of a tumor may be a promising weapon to stop triple negative breast cancer from metastasizing.

Cancer created Sep 19, 2012 | popularity 5 / 5 (1) | comments 0

Many cancer institution websites lack nutritional guidance, others give mixed messages

Radiation oncologists at Thomas Jefferson University Hospital are stressing the need for evidence-based, standardized guidelines on dietary recommendations for cancer patients—and with good reason. A new analysis revealed ...

Cancer created Mar 26, 2013 | popularity not rated yet | comments 0