A surprising form of cell-to-cell communication in glioblastoma promotes global changes in recipient cells, including aggressiveness, motility, and resistance to radiation or chemotherapy.
Jun 21, 2018
0
76
While mice can heal after a severe heart attack, an attack of the same severity in humans often launches a later descent into heart failure and death. Thus, study of the mouse healing may reveal therapeutic targets that can ...
Mar 6, 2018
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36
Research led by Ludwine Messiaen, Ph.D., professor of genetics at the University of Alabama at Birmingham, shows that missense mutations in a cluster of just five codons in the NF1 gene are an important risk factor for severe ...
Dec 28, 2017
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113
University of Alabama at Birmingham biomedical engineers report a significant advance in efforts to repair a damaged heart after a heart attack, using grafted heart-muscle cells to create a repair patch. The key was overexpressing ...
Oct 17, 2017
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433
Seizure disorders—including epilepsy—are associated with pathological hyperexcitability in brain neurons. Unfortunately, there are limited available treatments that can prevent this hyperexcitability. However, University ...
Oct 14, 2017
1
904
The key weapon against viruses and bacteria that invade the body is production of antibodies, which act like guided missiles to attack and neutralize pathogens.
Oct 2, 2017
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654
A major health problem in older people is age-associated osteoporosis—the thinning of bone and the loss of bone density that increases the risk of fractures. Often this is accompanied by an increase in fat cells in the ...
Sep 22, 2017
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142
The 200 different types of cells in the body all start with the same DNA genome. To differentiate into families of bone cells, muscle cells, blood cells, neurons and the rest, differing gene programs have to be turned on ...
Aug 15, 2017
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60
Changes in growth hormone levels during the early stages of development can have a long-lasting effect on lifespan, especially in males, according to new findings from the University of Alabama at Birmingham.
Jul 6, 2017
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20
Patients with colon and rectal cancer have somatic insertions of mitochondrial DNA into the nuclear genomes of the cancer cells, University of Alabama at Birmingham researchers report in the journal Genome Medicine.
Apr 12, 2017
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7
