University of California, Irvine

Medical research

Common tumor inhibitor drug triggers unfavorable immune effects

Cancer immunotherapy involving drugs that inhibit CTLA-4 also activates an unwanted response that may self-limit its efficacy in fighting tumors, according to a new study led by Francesco Marangoni, Ph.D., assistant professor ...

Genetics

Study sheds light on mysterious genotype-phenotype associations

A new study analyzing the association between an individual's genetics (genotype) and their observable characteristics resulting from the interaction of genetics and the environment (phenotype), contributes new knowledge ...

Diseases, Conditions, Syndromes

Study offers new approach for more accurate epidemic modeling

A new class of epidemiological models based on alternative thinking about how contagions propagate, particularly in the early phases of a pandemic, provide a blueprint for more accurate epidemic modeling and improved disease ...

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