University of Pennsylvania

Medications

Managing pain in the age of opioids

The data supporting the use of opioids to treat chronic, non-cancer pain is quite weak, says Michael Ashburn, director of the Penn Pain Medicine Center at the Perelman School of Medicine. As few as one in five patients may ...

Immunology

Answers to microbiome mysteries in the gills of rainbow trout

While many immunologists use mouse models to conduct their research, J. Oriol Sunyer of Penn's School of Veterinary Medicine has made transformational scientific insights using a very different creature: rainbow trout.

Diseases, Conditions, Syndromes

A roadblock for disease-causing parasites

The thread-like parasite Dirofilaria immitis, causes canine heartworm, a debilitating disease in dogs. A related parasite, Brugia malayi, infects humans and is one of the parasites responsible for lymphatic filariasis, a ...

Medical research

Predicting treatment outcome for leishmaniasis

For patients with cutaneous leishmaniasis, a skin infection transmitted by a sand fly that can in some cases lead to painful and disfiguring ulcers, treatment can be grueling. The first-line therapy offered to many requires ...

Genetics

Identifying a gene for canine night blindness

Creating an effective gene therapy for inherited diseases requires three key steps. First, scientists must identify and characterize the disease. Second, they must find the gene responsible. And finally, they must find a ...

Neuroscience

 A model for brain activity during brain stimulation therapy

Brain stimulation, where targeted electrical impulses are directly applied to a patient's brain, is already an effective therapy for depression, epilepsy, Parkinson's and other neurological disorders, but many more applications ...

Health

Slower growth in working memory linked to teen driving crashes

Research into why adolescent drivers are involved in motor vehicle crashes, the leading cause of injury and death among 16- to 19-year-olds in the United States, has often focused on driving experience and skills. But a new ...

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