University of Zurich

Diseases, Conditions, Syndromes

New insights into kidney disease using tropical frog models

Using cutting-edge genetic engineering, UZH researchers have developed a model to study hereditary kidney disease with the help of tropical frogs. The method allows them to collect large amounts of data on anomalies, which ...

Immunology

Mechanism behind ineffective psoriasis drugs identified

Psoriasis is a chronic inflammatory autoimmune disease that manifests as red, scaly skin patches. There is no causal treatment for the disease, but the symptoms can be significantly alleviated with modern therapies. Complex ...

Medications

Antidepressants inhibit cancer growth in mice

Classic antidepressants could help improve modern cancer treatments. They slowed the growth of pancreatic and colon cancers in mice, and when combined with immunotherapy, they even stopped the cancer growth long-term. In ...

Medications

Tailoring treatment of patients with COPD

Patients with COPD are treated with drugs to improve the breathing ability in combination with inhaled corticosteroids to reduce the risk of acute worsening of the lung conditions. But the balance between reduced exacerbations ...

Medical research

Cholesterol levels sustainably lowered using base editing

Base editing is a novel gene editing approach that can precisely change individual building blocks in a DNA sequence. By installing such a point mutation in a specific gene, an international research team led by the University ...

Oncology & Cancer

New technology makes tumor eliminate itself

A new technology developed by UZH researchers enables the body to produce therapeutic agents on demand at the exact location where they are needed. The innovation could reduce the side effects of cancer therapy and may hold ...

Diseases, Conditions, Syndromes

Biomarker detects severe COVID-19 early on

Severe cases of COVID-19 can now be detected at an early stage. Researchers at the University of Zurich have identified the first biomarker that can reliably predict which patients will develop severe symptoms. This can help ...

Diseases, Conditions, Syndromes

Defective epithelial barriers linked to 2 billion chronic diseases

Humans are exposed to a variety of toxins and chemicals every day. According to the epithelial barrier hypothesis, exposure to many of these substances damages the epithelium, the thin layer of cells that covers the surface ...

Psychology & Psychiatry

Stress and mental health problems during first COVID-19-lockdown

Many people in Switzerland experienced considerable psychological distress during the first COVID-19 lockdown from mid-March to the end of April 2020. Researchers from the Department of Child and Adolescent Psychiatry and ...

Medical research

The first comprehensive single-cell atlas of human teeth

Researchers at the University Zurich have mapped the first complete atlas of single cells that make up the human teeth. Their research shows that the composition of human dental pulp and periodontium vary greatly. Their findings ...

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