Wellcome Trust Sanger Institute

Genetics

Open data on malaria genomes will help combat drug resistance

Genome variation data on more than 7,000 malaria parasites from 28 endemic countries is released today in Wellcome Open Research. It has been produced by MalariaGEN, a data-sharing network of groups around the world who are ...

Oncology & Cancer

New drug targets for childhood cancer neuroblastoma identified

The largest single cell study to date of the childhood cancer, neuroblastoma, has answered important questions about the genesis of the disease. The researchers from the Wellcome Sanger Institute, Great Ormond Street Hospital ...

Medical research

Developmental origins of eczema and psoriasis discovered

Scientists have created a highly detailed map of skin, which reveals that cellular processes from development are re-activated in cells from patients with inflammatory skin disease. The researchers from the Wellcome Sanger ...

Immunology

Novel map reveals how immune cells fight and remember infections

Researchers have charted the activity of tens of thousands of genes in mouse immune cells over the course of an infection. The study from the University of Melbourne, Australia, the Wellcome Sanger Institute, and their collaborators ...

Medical research

DNA changes in healthy bladder provide clues on how cancer arises

The first comprehensive study of DNA changes in healthy and diseased human bladder tissue has revealed that 'cancer-driving' mutations are common in healthy bladder tissue. The study, conducted by scientists at the Wellcome ...

Diseases, Conditions, Syndromes

Cause of 1990s Argentina cholera epidemic uncovered

The evolution of epidemic and endemic strains of the cholera-causing bacterium Vibrio cholerae in Argentina has been mapped in detail by researchers at the Wellcome Sanger Institute, the London School of Hygiene and Tropical ...

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