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Genetics

Placenta is a dumping ground for genetic defects

In the first study of the genomic architecture of the human placenta, scientists at the Wellcome Sanger Institute, the University of Cambridge and their collaborators have confirmed that the normal structure of the placenta ...

Oncology & Cancer

11,000-year-old living dog cancer reveals its secrets

Scientists have sequenced the genome of the world's oldest continuously surviving cancer, a transmissible genital cancer that affects dogs. This cancer, which causes grotesque genital tumours in dogs around the world, first ...

Medical research

New hope for kidney cancer treatment using existing drugs

The most comprehensive study of kidney cancer at single-cell level has discovered a potential drug target to treat renal cell carcinoma, a cancer with a high mortality rate that is hard to detect. Researchers from the Wellcome ...

Oncology & Cancer

New cancer drug targets accelerate path to precision medicine

In one of the largest studies of its kind, researchers used CRISPR technology to disrupt every gene in over 300 cancer models from 30 cancer types and discover thousands of key genes essential for cancer's survival. The team, ...

Oncology & Cancer

Novel breast cancer gene found

A new study identifies a gene that is especially active in aggressive subtypes of breast cancer. The research suggests that an overactive BCL11A gene drives triple-negative breast cancer development and progression.

Oncology & Cancer

Red hair gene variation drives up skin cancer mutations

For the first time, researchers at the Wellcome Trust Sanger Institute and University of Leeds have proved that gene variants associated with red hair, pale skin and freckles are linked to a higher number of genetic mutations ...

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