News tagged with abnormal changes


FDA warning against high dose antidepressant prescription may be unwarranted, study finds

The U.S. Food and Drug Administration's warning that high doses of the antidepressant citalopram can cause potentially serious abnormal heart rhythms might be doing more harm than good.

Psychology & Psychiatry created May 03, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Machine similar to dialysis removes cholesterol from blood

Some patients are genetically prone to such dangerously high levels of cholesterol that no amount of diet, exercise and medications can reduce their cholesterol to safe levels.

Other created Mar 01, 2013 | popularity not rated yet | comments 1

Epigenomic abnormalities predict patient survival in non-Hodgkins lymphoma

Think of the epigenome like a giant musical mixing board, turning up or down the expression of various genes. A University of Colorado Cancer Center study published today in the journal PLOS Genetics shows that in cancer ...

Genetics created Jan 10, 2013 | popularity not rated yet | comments 0 | with audio podcast

Alzheimer's disease in mice alleviated promising therapeutic approach for humans

Pathological changes typical of Alzheimer's disease were significantly reduced in mice by blockade of an immune system transmitter. A research team from Charité - Universitätsmedizin Berlin and the University ...

Alzheimer's disease & dementia created Nov 25, 2012 | popularity 5 / 5 (10) | comments 0 | with audio podcast

Discovery of molecular pathway of Alzheimer's disease reveals new drug targets

The discovery of the molecular pathway that drives the changes seen in the brains of Alzheimer's patients is reported today, revealing new targets for drug discovery that could be exploited to combat the disease. The study ...

Alzheimer's disease & dementia created Nov 20, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

First evidence for genetic cause for Barrett's oesophagus found

Genetic variations that are linked with the onset of Barrett's oesophagus (BE), a pre-cancerous condition of the lower end of the gullet, have been identified for the first time. The discovery of variations in regions on ...

Genetics created Sep 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Treatment for cervical disease is not linked to increased risk of preterm births

Treatment for cervical disease does not appear to increase the risk of subsequently giving birth prematurely, according to a study of over 44,000 women in England. The study, published online in the British Medical Journal today, ...

Obstetrics & gynaecology created Aug 16, 2012 | popularity not rated yet | comments 0 | with audio podcast

Largest review of management and treatment of Barrett's dysplasia and adenocarcinoma

The world's largest review of all the evidence on the best way of managing and treating common pre-cancerous and cancerous conditions of the oesophagus (gullet) has found that good endoscopy equipment, more endoscopic surgery, ...

Diseases, Conditions, Syndromes created Jul 23, 2012 | popularity 5 / 5 (1) | comments 0

Telomere failure, telomerase activation drive prostate cancer progression

Genomic instability caused by an erosion of the protective caps on chromosomes, followed by activation of an enzyme that reinforces those caps, allows malignant cells to evade destruction and acquire more deadly characteristics, ...

Cancer created Feb 21, 2012 | popularity 4 / 5 (1) | comments 0

Study examines drug resistance in ALK positive lung cancer

Scientists from the University of Colorado Cancer Center have once again advanced the treatment of a specific kind of lung cancer. The team has documented how anaplastic lymphoma kinase (ALK) positive advanced non-small cell ...

Cancer created Jan 19, 2012 | popularity not rated yet | comments 0

How the brain puts the brakes on the negative impact of cocaine

Research published by Cell Press in the January 12 issue of the journal Neuron provides fascinating insight into a newly discovered brain mechanism that limits the rewarding impact of cocaine. The study describes protective delaye ...

Neuroscience created Jan 11, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Genetic testing for inherited cardiac conditions is 'patchy' in Europe

While genetic inheritance is known to play a role in the multifactorial development of most diseases of the heart, there are also a number of clearly diagnosed cardiac conditions which owe their development to quite specific ...

Cardiology created Jun 27, 2011 | popularity not rated yet | comments 0