Therapies for ALL and AML targeting MER receptor hold promise of more effect with less side-effect
Two University of Colorado Cancer Center studies show that the protein receptor Mer is overexpressed in many leukemias, and that inhibition of this Mer receptor results in the death of leukemia cells – without affecting ...
Cancer
Mar 11, 2013 |
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Researchers identify genetic variation behind acute myeloid leukemia treatment success
Researchers from the College of Pharmacy and Medical School working within the Masonic Cancer Center, University of Minnesota, have partnered to identify genetic variations that may help signal which acute myeloid leukemia ...
Cancer
Feb 26, 2013 |
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Stem cell survival strategy key to blood and immune system health
Stem cells of the aging bone marrow recycle their own molecules to survive and keep replenishing the blood and immune systems as the body ages, researchers at UC San Francisco (UCSF) have discovered.
Medical research
Feb 14, 2013 |
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Risk of leukemia after cancer chemotherapy persists
While advancements in cancer treatment over the last several decades have improved patient survival rates for certain cancers, some patients remain at risk of developing treatment-related leukemia, according to results of ...
Cancer
Feb 14, 2013 |
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Researchers identify new strategy for interfering with potent cancer-causing gene
Acute myeloid leukemia (AML) is an aggressive blood cancer that is currently incurable in 70% of patients. In a bold effort, CSHL scientists are among those identifying and characterizing the molecular mechanisms responsible ...
Cancer
Feb 11, 2013 |
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Study suggests improved treatment alternative for lymphoid leukemia
Discovering what they call the "Achilles' heel" for lymphoid leukemia, an international research team has tested a possible alternative treatment that eradicated the disease in mouse models.
Cancer
Feb 11, 2013 |
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Researchers use new molecular inhibitors to successfully hit difficult cancer target
Early laboratory tests are the first to successfully use an experimental molecular therapy to block a hard-to-target part of a protein complex linked to several types of invasive cancer.
Cancer
Feb 05, 2013 |
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Study finds mutations linked to relapse of childhood leukemia
After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked ...
Genetics
Feb 03, 2013 |
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Gleevec's latest approval is for pediatric cancer
(HealthDay)—The anti-cancer drug Gleevec (imatinib) has received new U.S. Food and Drug Administration approval to treat the most common type of pediatric cancer, affecting some 2,900 children each year, the agency said ...
Cancer
Jan 25, 2013 |
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Study finds new genetic defects in high-risk childhood leukemia subtypes with chromosomal loss
Research led by St. Jude Children's Research Hospital scientists has identified a possible lead in treatment of two childhood leukemia subtypes known for their dramatic loss of chromosomes and poor treatment outcomes.
Genetics
Jan 20, 2013 |
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Study of cancer cell metabolism yields new insights on leukemia
University of Rochester Medical Center scientists have proposed a new reason why acute myeloid leukemia, one of the most aggressive cancers, is so difficult to cure: a subset of cells that drive the disease appear to have ...
Cancer
Jan 17, 2013 |
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Alkylating agent linked to therapy-related leukemia
(HealthDay)—For patients treated for Hodgkin's lymphoma (HL), cumulative doses of alkylating agent (AA) is associated with the risk of therapy-related acute myeloid leukemia/myelodysplastic syndrome (t-AML/MDS), ...
Cancer
Jan 15, 2013 |
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ASH international clinical collaboration replicates high cure rate of APL in developing countries
Data published online today in Blood, the Journal of the American Society of Hematology (ASH) describe the work of an ASH international clinical network collaborative focused on modernizing treatment protocols for patien ...
Cancer
Jan 14, 2013 |
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Scientists shed new light on mechanisms of T-ALL, a form of leukemia that primarily affects children
Acute lymphatic leukemia (ALL) is the most common cancer in children under the age of 14 years. With optimum treatment, approximately 75 % of children are currently cured, but the treatment consists of severe chemotherapy ...
Cancer
Dec 23, 2012 |
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Options increase for CML patients failed by existing drugs
The U.S. Food and Drug Administration (FDA) this month expanded the options for patients with chronic myeloid leukemia and one form of acute lymphoblastic leukemia that carries the Philadelphia chromosome (Ph+ALL). It approved ...
Cancer
Dec 21, 2012 |
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