Oncology & Cancer

New understanding of how faulty metabolism triggers adrenal cancer

Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands. This discovery explains how impaired metabolism due to mutations in a key ...

Oncology & Cancer

Scientists develop urine test for cancer

Scientists at the University of Birmingham have developed a ground-breaking technique that uses a urine test to help to diagnose adrenal cancer.

Oncology & Cancer

Researchers identify an Achilles' heel in neuroblastoma

Neuroblastoma, a childhood cancer that develops from neural cells on the adrenal glands, accounts for 15% of childhood cancer deaths. Almost half of children with high-risk neuroblastoma harbor extra copies of the gene MYCN ...

Oncology & Cancer

New drug targets for childhood cancer neuroblastoma identified

The largest single cell study to date of the childhood cancer, neuroblastoma, has answered important questions about the genesis of the disease. The researchers from the Wellcome Sanger Institute, Great Ormond Street Hospital ...

Immunology

Why don't adrenal gland metastases respond to immunotherapy?

Recent advances in immunotherapy have allowed doctors at the University of Colorado Cancer Center to more effectively treat melanomas that spread to other parts of the body. Immunotherapy drugs such as checkpoint inhibitors, ...

Oncology & Cancer

New review identifies four hallmarks of cancer metastasis

Researchers at the University of Alabama at Birmingham and the University of Kansas Cancer Center have identified four hallmarks of cancer metastasis—when cancer has spread to different parts of the body from where it started. ...

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