Columbia University Medical Center (CUMC) researchers have captured the first three-dimensional snapshots of the AMPA-subtype glutamate receptor in action. The receptor, which regulates most electrical signaling in the brain, ...
Jul 24, 2017
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Our brains are made up of networks of neurons where each individual nerve cell can make connections with thousands of others. AMPA receptors are a set of membrane proteins that mediate fast signal transmission across these ...
Jun 3, 2021
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Synapses allow neurons to communicate with one another. In the synapse, one neuron emits chemical messengers called neurotransmitters, and an adjacent neuron receives them using tiny structures called receptors. A specific ...
Nov 20, 2019
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In a current paper published in the journal Nature, Heidelberg-based researchers and physicians describe how neurons in the brain establish contact with aggressive glioblastomas and thus promote tumor growth / New tumor activation ...
Sep 20, 2019
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Early-life seizures prematurely switch on key synapses in the brain that may contribute to further neurodevelopmental delay in children with autism and other intellectual disabilities, suggests a new study from researchers ...
May 29, 2018
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Scientists at Columbia University have obtained the first detailed images of interactions between the AMPA receptor and molecules that regulate chemical signaling in the brain. Their findings may help understand the processes ...
May 3, 2017
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As many as one out of four adults who suffer from epilepsy do not respond to any available drugs.
Nov 29, 2016
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Surprisingly complex interactions between neurotransmitter receptors and other key proteins help explain the brain's ability to process information with lightning speed, according to a new study.
Feb 25, 2016
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A tiny piece of a critical receptor that fuels the brain and without which sentient beings cannot live has been discovered by University at Buffalo scientists as a promising new drug target for Alzheimer's and other neurodegenerative ...
Oct 11, 2011
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Sporadic amyotrophic lateral sclerosis (ALS) accounts for 90% of all ALS cases. Researchers from the University of Tsukuba discovered that the editing efficiency at the glutamine/arginine (Q/R) site of GluA2 messenger RNA ...
May 23, 2023
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