A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of Alzheimer's disease, a new study shows.
Jun 15, 2021
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Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process.
Jun 14, 2021
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Researchers at the Biomedicine Institute of Seville (IBiS) have discovered a new mechanism of Alzheimer's disease that disorganizes the blood vessels around amyloid plaques, one of the characteristic features of the disease. ...
May 31, 2021
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Alzheimer's disease is the most common form of dementia and is characterized by the build-up of amyloid plaques in the brain. Microglia, the immune sentinels of the brain, are not only responsible for eliminating foreign ...
May 21, 2021
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Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer's disease (AD), a key step toward eventually ...
May 5, 2021
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One of the characteristic hallmarks of Alzheimer's disease (AD) is the buildup of amyloid-beta plaques in the brain. Most therapies designed to treat AD target these plaques, but they've largely failed in clinical trials. ...
Apr 15, 2021
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A small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the brains of Alzheimer's disease patients. If perfected in humans, the technique could ...
Apr 13, 2021
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As people age, a normal brain protein known as amyloid beta often starts to collect into harmful amyloid plaques in the brain. Such plaques can be the first step on the path to Alzheimer's dementia. When they form around ...
Feb 17, 2021
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The older we grow, the weaker our muscles get, riddling old age with frailty and physical disability. But this doesn't only affect the individual, it also creates a significant burden on public healthcare. And yet, research ...
Jan 19, 2021
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Fractured sleep, daytime sleepiness and other signs of disturbance in one's circadian rhythm are common complaints of people with Alzheimer's disease, and the problems only get worse as the disease progresses. But the reason ...
Dec 16, 2020
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