Diseases, Conditions, Syndromes

Serum free light chain level increase precedes amyloidosis

(HealthDay)—Increased serum free light chains (FLCs) precede the presentation of immunoglobulin light chain amyloidosis (AL amyloidosis), according to a study published online July 14 in the Journal of Clinical Oncology.

Genetics

Fatal overproduction of antibodies

Bone marrow plasma cells produce antibodies. These comprise two long and two short protein chains. The pathological proliferation of plasma cells can lead to an overproduction of the short chains. These associate to fibrils ...

Alzheimer's disease & dementia

Researchers uncover novel amyloidosis

A collaboration led by scientists at Tokyo University of Agriculture and Technology (TUAT), Japan, has discovered a novel amyloid protein that induces amyloidosis in rats. This new amyloid protein is known to be the lipopolysaccharide ...

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