Neuroscience

Profound loss of pleasure related to early-onset dementia

People with early-onset dementia are often mistaken for having depression and now Australian research has discovered the cause: a profound loss of ability to experience pleasure—for example a delicious meal or beautiful ...

Psychology & Psychiatry

Genetic variation contributes to individual differences in pleasure

Differences in how our brains respond when we're anticipating a financial reward are due, in part, to genetic differences, according to research with identical and fraternal twins published in Psychological Science, a journal ...

Medications

New drug mimics benefits of ketamine for depression

A new small-molecule drug produced a rapid antidepressant response similar to that of ketamine when tested in mice, a new Yale-led study published April 16 in the Journal of Clinical Investigation shows.

Psychology & Psychiatry

People with anhedonia do experience pleasure, just not as often

Put bluntly, a hedonist is a bon vivant, or at the very least somebody whose highest priority is to enjoy life. If you suffer from anhedonia – the opposite of this – then you are in an unenviable position. During her ...

Neuroscience

Why stress doesn't always cause depression

Rats susceptible to anhedonia, a core symptom of depression, possess more serotonin neurons after being exposed to chronic stress, but the effect can be reversed through amygdala activation, according to new research in the ...

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