HIV & AIDS

Immunotherapy combo achieves reservoir shrinkage in HIV model

Stimulating immune cells with two cancer immunotherapies together can shrink the size of the viral "reservoir" in SIV-infected non-human primates treated with antiviral drugs, researchers have concluded. The reservoir includes ...

Immunology

Second DNA-sensing pathway in humans discovered

A team of researchers at Washington State University has discovered a second DNA-sensing pathway that initiates an antiviral response to foreign genetic material in human cells. In their paper published in the journal Science ...

HIV & AIDS

Researchers find new clues to controlling HIV

The immune system is the body's best defense in fighting diseases like HIV and cancer. Now, an international team of researchers is harnessing the immune system to reveal new clues that may help in efforts to produce an HIV ...

Immunology

Research could lead to better vaccines and new antivirals

Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a new regulator of the innate immune response—the immediate, natural immune response to foreign invaders. The study, published recently ...

Oncology & Cancer

T cell revival through PD-1: Clues for cancer immunotherapy

Cancer immunotherapy drugs that block the inhibitory PD-1 pathway have shown success in clinical trials and are now FDA-approved for melanoma, lung cancer and bladder cancer. Yet many patients' tumors do not respond to these ...

Immunology

'Key' to recognizing and immunizing herpes, common cold

Researchers at McMaster University have discovered a critical step in the immune system's recognition of DNA viruses. It's a key finding, they say, that could lead to vaccinations for herpes, the common cold or even cancer.

Immunology

Research team uncovers genetic trigger for immune response

The thousands of mitochondrial DNA (mtDNA) molecules present in each cell are known primarily for their role converting food and oxygen into energy. But Yale researchers have identified an unexpected relationship between ...

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