Oncology & Cancer

Membrane around tumors may be key to preventing metastasis

For cancer cells to metastasize, they must first break free of a tumor's own defenses. Most tumors are sheathed in a protective "basement" membrane—a thin, pliable film that holds cancer cells in place as they grow and ...

Genetics

Genetic mutations may be linked to infertility, early menopause

A new study from Washington University School of Medicine in St. Louis identifies a specific gene's previously unknown role in fertility. When the gene is missing in fruit flies, roundworms, zebrafish and mice, the animals ...

Medical research

A bacterial toxin turning cells into swiss cheese

Although the innate immune system is the front line of defense against microbial infections, the complex mechanisms of innate immunity are incompletely understood. In a new study, researchers from Kanazawa University synthesized ...

Immunology

Antibodies gather and form a circle for defensive attack

Antibodies play a crucial role in our immune system by linking antigen recognition with complement activation for attacking foreign cells. Using high-speed atomic force microscopy, collaborative groups, including researchers ...

Medical research

Figuring out Alzheimer's

One of the tasks of scientists' work is to explain how the world functions. Their research ideas may often seem unrealistic but, as it turns out, their research may truly help a great many of us.

Immunology

It's Fab! A hidden touch of antibody

In our immune system, antibodies recognize viruses, bacteria and even cancer cells through their Fab arms, initiating recruitment of leucocytes for the destruction of these invaders. The recruitment is mediated by receptors ...

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