Immunology

A switch for autoimmunity

When a virus or bacteria comes calling, protein "sensors" in your cells can detect the invader's DNA and activate inflammatory responses to prevent infection. One such sensor is cGAS (cyclic GMP-AMP synthase).

Immunology

Finding what fuels the 'runaway train' of autoimmune disease

A newly-unveiled discovery, which has been four years in the making, has the potential to change the way we look at autoimmune diseases and understand how and why immune cells begin to attack different tissues in the body.

Immunology

Clustering for health

When functioning appropriately, the immune system protects against multiple threats such as pathogens, disease-causing microbes, and tumors. However, when the immune system is inappropriately activated, it attacks the body, ...

Immunology

Study describes key RNA epigenetic marker's role in immune system

The white blood cells known as T cells regulate our body's response to foreign substances—our adaptive immune response. In a new study, Yale scientists have learned how changes in a recently discovered RNA epigenetic marker ...

Immunology

Master detox molecule boosts immune defenses

Scientists at the Luxembourg Institute of Health (LIH) have discovered hitherto unknown molecular mechanism by which the human immune system activates its immune cells. T cells that express a gene known as Gclc effectively ...

Immunology

Altering the immune system to reverse paralysis

In the ultimate betrayal, one's own immune system can turn against the protective sheath that envelops neurons in the brain, leaving the body paralyzed. Researchers have developed an experimental treatment that tames the ...

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