Genetics

Scientists map genes controlling immune system 'brakes'

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed. Now, researchers ...

Medical research

Type 1 diabetes from a beta cell's perspective

Type 1 diabetes is an autoimmune disease that occurs when T-cells in the immune system attack the body's own insulin-producing cells, called beta cells, in the pancreas. Usually diagnosed in children and young adults, type ...

HIV & AIDS

Existing drugs may limit damage caused by HIV

Yale researchers have identified four drugs that may help minimize the long-term health effects of HIV infection, they report June 23 in the Journal of Clinical Investigation.

Medical research

Probing innate immunity, cGAS protein, and our own damaged DNA

The protein cGAS plays an essential role in cellular innate immunity by detecting the DNA of invading pathogens such as bacteria and viruses, or our own damaged and mislocalized DNA. Activation of the cGAS-STING signaling ...

Immunology

The microbiome controls immune system fitness

Working alongside colleagues in Mainz, Bern, Hannover and Bonn, researchers from Charité - Universitätsmedizin Berlin, the Berlin Institute of Health (BIH) and the German Rheumatism Research Center Berlin (DRFZ) were able ...

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