News tagged with b cell
New protein-targeting drug shows promise in early trial for patients with high-risk CLL
A new oral targeted drug, idelalisib (GS-1101), has the potential to stave off the need for additional treatments for relapsed or treatment-resistant chronic lymphocytic leukemia (CLL), according to a study led in part by ...
Cancer
May 17, 2013 |
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Gold nanoparticles show new way to kill lymphoma without chemotherapy
How do you annihilate lymphoma without using any drugs? Starve it to death by depriving it of what appears to be a favorite food: HDL cholesterol.
Cancer
Jan 21, 2013 |
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New vaccine-design approach targets HIV and other fast-mutating viruses
A team led by scientists from The Scripps Research Institute (TSRI) and the International AIDS Vaccine Initiative (IAVI) has unveiled a new technique for vaccine design that could be particularly useful against ...
HIV & AIDS
Mar 28, 2013 |
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Knowing origin of broadly neutralizing antibodies could aid universal flu vaccine design
National Institutes of Health scientists have identified how a kind of immature immune cell responds to a part of influenza virus and have traced the path those cells take to generate antibodies that can neutralize a wide ...
Medical research
Aug 29, 2012 |
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New immune therapy treats brain tumors in mice
Using an artificial protein that stimulates the body's natural immune system to fight cancer, a research team at Duke Medicine has engineered a lethal weapon that kills brain tumors in mice while sparing ...
Immunology
Dec 17, 2012 |
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Study finds how to shutdown cancer's powerful master protein
The powerful master regulatory transcription factor called Bcl6 is key to the survival of a majority of aggressive lymphomas, which arise from the B-cells of the immune system. The protein has long been considered too complex ...
Immunology
Mar 03, 2013 |
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Evolution in the antibody factory: How immune cells are able to advance their own evolution
Immune system B cells play a crucial role in the defence of pathogens; when they detect such an intruder, they produce antibodies that help to combat the enemy. They concurrently and continuously improve ...
Immunology
Mar 11, 2013 |
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A single protein helps the body keep watch over the Epstein-Barr virus
Some 90 percent of people are exposed to the Epstein Barr virus (EBV) at some point in their life. Even though it is quickly cleared from the body, the virus can linger silently for years in small numbers of infected B cells. ...
Medical research
Feb 17, 2012 |
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Study finds interferon, one of the body's proteins, induces persistent viral infection
Scientists at The Scripps Research Institute (TSRI) have made a counterintuitive finding that may lead to new ways to clear persistent infection that is the hallmark of such diseases as AIDS, hepatitis B and hepatitis C.
Medical research
Apr 11, 2013 |
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Ills of aging blood: Short-circuited stem cell programming linked to failing blood development
As blood stem cells age, changes in the epigenome—the system that regulates which genes are switched on and which are switched off throughout the body—alter these cells in ways that lead to reduced immune ...
Medical research
Feb 15, 2013 |
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Monoclonal antibody targets, kills leukemia cells
Researchers at the University of California, San Diego Moores Cancer Center have identified a humanized monoclonal antibody that targets and directly kills chronic lymphocytic leukemia (CLL) cells.
Cancer
Mar 25, 2013 |
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Immune system molecule with hidden talents
Dendritic cells, or DCs for short, perform a vital role for the immune system: They engulf pathogens, break them down into their component parts, and then display the pieces on their surface. This in turn ...
Immunology
Jan 22, 2013 |
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After three decades of searching, scientists find cellular targets of Hepatitis B virus
A University of Colorado Boulder-led team has discovered two prime targets of the Hepatitis B virus in liver cells, findings that could lead to treatment of liver disease in some of the 400 million people worldwide currently ...
Diseases, Conditions, Syndromes
Oct 22, 2012 |
3.7 / 5 (3) |
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How the body uses vitamin B to recognize bacterial infection
An Australian research team has discovered how specialised immune cells recognise products of vitamin B synthesis that are unique to bacteria and yeast, triggering the body to fight infection.
Medical research
Oct 10, 2012 |
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Genome sequencing of Burkitt Lymphoma reveals unique mutation
In the first broad genetic landscape mapped of a Burkitt lymphoma tumor, scientists at Duke Medicine and their collaborators identified 70 mutations, including several that had not previously been associated with cancer and ...
Genetics
Nov 12, 2012 |
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