Inflammatory disorders
Cluster of new studies reveal how gut microbes work to tame intestinal inflammation
Bile acids made by the liver have long been known for their critical role in helping to absorb the food we ingest.
Mar 16, 2022
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News tagged with bile acid
Diabetes
A drug that does double duty in treating diabetes
Yale researchers have developed an oral medication to treat diabetes that controls insulin levels while simultaneously reversing the inflammatory effects of the disease.
Nov 16, 2021
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174
Diseases, Conditions, Syndromes
Organoid success reveals potential target for future treatment of biliary atresia
Biliary atresia is the largest cause of end-stage liver fibrosis in children and the main reason children need liver transplants. Despite many years of worldwide research, scientists have not yet found a way to prevent the ...
Sep 7, 2021
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Gastroenterology
Scientists discover new role for bile acids: They curb appetite by entering the brain
EPFL scientists have discovered a new role for bile acids: they curb appetite by entering the brain. Their findings, which were recently published in Nature Metabolism, provide new insights into the signals and mechanisms ...
May 24, 2021
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Diseases, Conditions, Syndromes
Crohn's disease may be caused by immune signaling failure
People with Crohn's disease are typically treated with powerful anti-inflammatory medications that act throughout their body, not just in their digestive tract, creating the potential for unintended, and often serious, side ...
Apr 7, 2021
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117
Medical research
Lab-grown miniature human livers successfully transplanted in rats
Using skin cells from human volunteers, researchers at the University of Pittsburgh School of Medicine have created fully functional mini livers, which they then transplanted into rats.
Jun 2, 2020
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202
Medical research
Study reveals bile metabolite of gut microbes boosts immune cells
A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells—immune cells that suppress autoimmune reactions and inflammation. ...
Apr 16, 2020
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419
Medical research
Cellular stress makes obese mothers have obese babies
Maternal obesity increases the risk for obesity and metabolic perturbations in their offspring, but what are the mechanisms? In a new study published March 12 in the open-access journal PLOS Biology, Sebastien Bouret of the ...
Mar 16, 2020
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Medical research
How resident microbes restructure body chemistry
The makeup of our microbiomes—the unique communities of bacteria, viruses and other microbes that live in and on us—have been linked, with varying degrees of evidence, to everything from inflammatory bowel disease to ...
Feb 26, 2020
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98
Diabetes
Study finds tiny 'nano' capsules effective in treating type two diabetes
Curtin University researchers have developed tiny capsules that are able to effectively target the liver and pancreas reducing the inflammatory effects of type two diabetes.
Jan 13, 2020
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